(1R,5S)-8-(2-Fluoro-4-nitrophenyl)-8-azabicyclo[3.2.1]octan-3-one

被引：0

作者：

Yang, Tao ^{[1
]}

Yang, Jianzhong ^{[1
]}

Li, Zicheng ^{[2
]}

Luo, Youfu ^{[1
]}

机构：

[1] Sichuan Univ, W China Hosp, State Key Lab Biotherapy, Chengdu 610041, Peoples R China

[2] Sichuan Univ, Sch Chem Engn, Dept Pharmaceut & Bioengn, Chengdu 610065, Peoples R China

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2011年 / 67卷

关键词：

data-to-parameter ratio = 11.5; disorder in main residue; mean σ(C-C) = 0.003 Å; R factor = 0.044; single-crystal X-ray study; T = 293 K; wR factor = 0.113;

D O I：

10.1107/S1600536811047350

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

In the title compound, C13H13FN2O3, the fused piperidine ring is in a chair conformation. The fused pyrrolidine ring shows an envelope conformation with the N atom displaced by 0.661 (3) angstrom out of the plane formed by the four C atoms of the pyrrolidine ring. The dihedral angle between this plane and the plane formed by the four attached C atoms of the piperidine ring (not including the carbonyl C atom) is 67.63 (10)degrees. The F atom is disordered and was refined using a split model with an occupancy ratio of 0.910 (3): 0.080 (3).

引用

页码：O3297 / U1809

页数：8

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← 1 2 3 4 5 →

(1R*,5S*)-8-(2-Fluoro-4-nitrophenyl)-8-azabicyclo[3.2.1]octan-3-one

(1R,5S)-8-(2-Fluoro-4-nitrophenyl)-8-azabicyclo[3.2.1]octan-3-one