(2R)-8-Benzyl-2-[(S)-hydroxy(phenyl)methyl]-8-azabicyclo[3.2.1]octan-3-one

被引：6
|
作者：
Brzezinski, Krzysztof [1 ]
Lazny, Ryszard [2 ]
Sienkiewicz, Michal [2 ]
Wojtulewski, Slawomir [2 ]
Dauter, Zbigniew [1 ]
机构：
[1] NCI, Synchrotron Radiat Res Sect, MCL, Argonne Natl Lab,Biosci Div, Argonne, IL 60439 USA
[2] Univ Bialystok, Inst Chem, PL-15399 Bialystok, Poland
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2012年 / 68卷
基金：
美国国家卫生研究院;
关键词：
ALDOL;
D O I：
10.1107/S1600536811053190
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The crystal of the title compound, C21H23NO2, was chosen from a conglomerate formed by a racemic mixture. An intramolecular hydrogen bond is formed between hydroxy group and heterocyclic N atom of the azabicyclo[ 3.2.1] octan-3-one system. The crystal structure is stabilized by C-H center dot center dot center dot O interactions between aliphatic C-H groups and the carbonyl O atom. For the title chiral crystal, the highly redundant and accurate diffraction data set collected with low energy copper radiation gave a Flack parameter of 0.12 (18) for anomalous scattering effects originating from O atoms.
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页数：11
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