Methyl 2,2′-dimethyl-4′-[2-(methylsulfanyl)ethyl]-1,3-dioxo-2,3-dihydro-1H,4′H-spiro[isoquinoline-4,5′-oxazole]-4′-carboxylate

被引：0
|
作者：
Fun, Hoong-Kun [1 ]
Quah, Ching Kheng [1 ]
Huang, Chengmei [2 ]
Yu, Haitao [2 ]
机构：
[1] Univ Sains Malaysia, Xray Crystallog Unit, Sch Phys, Usm 11800, Penang, Malaysia
[2] Nanjing Univ, Sch Chem & Chem Engn, Nanjing 210093, Peoples R China
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2011年 / 67卷
关键词：
X-RAY; DIFFRACTION; INHIBITORS; DISCOVERY;
D O I：
10.1107/S1600536811030133
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
In the isoquinoline ring system of the title molecule, C18H20N2O5S, the fused N-heterocyclic ring is distorted towards a half-boat conformation. The methyl formate moiety is disordered over two sets of sites with refined occupancies of 0.882 (5) and 0.118 (5). In the crystal, molecules are linked via weak intermolecular C-H center dot center dot center dot O hydrogen bonds into one-dimensional chains along [010].
引用
收藏
页码：O2216 / U1579
页数：13
相关论文
共 50 条
  • [21] Spiro heterocyclization of methyl 4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates with acyclic enamino ketones
    Yu. N. Bannikova
    V. V. Khalturina
    E. A. Sedegova
    A. N. Maslivets
    Russian Journal of Organic Chemistry, 2007, 43 : 154 - 155
  • [22] Spiro heterocyclization of methyl 4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates with acyclic enamino ketones
    Bannikova, Yu. N.
    Khalturina, V. V.
    Sedegova, E. A.
    Maslivets, A. N.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2007, 43 (01) : 154 - 155
  • [23] Ethyl N-(2-butyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)carbamate
    Shi, DX
    Feng, YQ
    Li, XF
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2003, 59 : O739 - O741
  • [24] 2-(3-Methyl-2-nitrophenyl)-4,5-dihydro-1,3-oxazole
    Lei, Dongwei
    Yang, Huibin
    Li, Bin
    Kang, Zhuo
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O54 - U1725
  • [25] Synthesis,Crystal Structure and Anti-fungal Activity of 2-(4-Chlorophenyl)-(1,3-dimethyl-2,3-dihydro-1H)-perimidine
    袁霖
    李中燕
    张敏
    袁先友
    结构化学, 2016, 35 (08) : 1181 - 1185
  • [26] Synthesis of spiro[imidazole-2,2'-pyrroles] by reaction of 4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates with urea
    Dubovtsev, A. Yu.
    Silaichev, P. S.
    Zheleznova, M. A.
    Aliev, Z. G.
    Maslivets, A. N.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 52 (12) : 1779 - 1783
  • [27] Synthesis of spiro[imidazole-2,2′-pyrroles] by reaction of 4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates with urea
    A. Yu. Dubovtsev
    P. S. Silaichev
    M. A. Zheleznova
    Z. G. Aliev
    A. N. Maslivets
    Russian Journal of Organic Chemistry, 2016, 52 : 1779 - 1783
  • [28] 1′-methyl-2"-phenylcyclohexane-1-spiro-4′-[acenaphthene-1-spiro-2′-pyrrolidine-3′-spiro-4"(5"H)-[1,3]oxazole]-2,5"-dione
    Selvanayagam, S
    Velmurugan, D
    Ravikumar, K
    Jayashankaran, J
    Durga, RR
    Raghunathan, R
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2004, 60 : O2216 - O2218
  • [29] Ethyl 1′-[1-(4-methoxyphenyl)-3-phenoxy-4-phenylazetidin-1-yl]-1,3-dioxo-2′,3′,5′,6′,7′,7a′-hexahydroindan-2-spiro-3′-1′H-pyrrolizine-2′-carboxylate
    Kamala, E. Theboral Sugi
    Nirmala, S.
    Sudha, L.
    Arumugam, N.
    Raghunathan, R.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1832 - U2613
  • [30] An efficient synthesis of 1′,4′-dihydro-2′H-spiro[azetidin-2,3′-quinolin]-2′-one
    Longjiang Huang
    Yuan Tian
    Dawei Teng
    Research on Chemical Intermediates, 2017, 43 : 219 - 228
12345