Haemolytic Activity and Immunological Adjuvant Effect of a New Steroidal Saponin from Allium ampeloprasum var. porrum

被引：19
|
作者：
Adao, Camila Rodrigues [1 ]
da Silva, Bernadete Pereira [1 ]
Tinoco, Luzineide Wanderley [1 ]
Parente, Jose Paz [1 ]
机构：
[1] Univ Fed Rio de Janeiro, Ctr Ciencias Saude, Nucleo Pesquisas Prod Nat, Lab Quim Plantas Med, BR-21941971 Rio De Janeiro, Brazil
来源：
CHEMISTRY & BIODIVERSITY | 2012年 / 9卷 / 01期
关键词：
Allium ampeloprasum var; porrum; Steroids; Saponins; Haemolytic activity; Immunological adjuvants; GAS-LIQUID CHROMATOGRAPHY; IMMUNE-RESPONSES; SAPOGENINS; OVALBUMIN; MICE; MONOSACCHARIDES; SPIROSTANE; ANTIGEN; PLANTS;
D O I：
10.1002/cbdv.201100005
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A new steroidal saponin was isolated from the bulbs of Allium ampeloprasum L. var. porrum. On the basis of chemical evidence, comprehensive spectroscopic analyses, and comparison with known compounds, its structure was established as (3 beta,5a,6 beta,25R)-3-{(O-beta-D-glucopyranosyl-(1?3)-beta-D-glucopyranosyl-(1?2)-O-[O-beta-D-glucopyranosyl-(1?3)]-O-beta-D-glucopyranosyl-(1?4)-beta-D-galactopyranosyl)oxy}-6-hydroxyspirostan-2-one (1). Results of the present study indicated that 1 exhibited haemolytic activity in the in vitro assays, and immunological adjuvant activity on the cellular immune response against ovalbumin antigen.
引用
收藏
页码：58 / 67
页数：10
相关论文
共 50 条
  • [21] Comparing the effect of several pretreatment steps, selected to steer (bio) chemical reactions, on the volatile profile of leek (Allium ampeloprasum var. porrum)
    Delbaere, Sophie M.
    Bernaerts, Tom
    Vancoillie, Flore
    Buve, Carolien
    Hendrickx, Marc E.
    Grauwet, Tara
    Loey, Ann M. Van
    LWT-FOOD SCIENCE AND TECHNOLOGY, 2022, 172
  • [22] Immunological Adjuvant Activity of Pectinioside A, the Steroidal Saponin from the Starfish Patiria pectinifera
    Kawase, Osamu
    Ohno, Osamu
    Suenaga, Kiyotake
    Xuan, Xuenan
    NATURAL PRODUCT COMMUNICATIONS, 2016, 11 (05) : 605 - 606
  • [23] A new complex triterpenoid saponin from Calliandra pulcherrima with haemolytic activity and adjuvant effect
    da Silva, Bernadete Pereira
    Parente, Jose Paz
    PHYTOCHEMISTRY LETTERS, 2013, 6 (04) : 633 - 639
  • [24] A new complex triterpenoid saponin from Samanea saman with haemolytic activity and adjuvant effect
    Barbosa, Antony de Paula
    da Silva, Bernadete Pereira
    Parente, Jose Paz
    PHYTOCHEMISTRY LETTERS, 2012, 5 (03) : 626 - 631
  • [25] Antioxidant changes during domestic food processing of the white shaft and green leaves of leek (Allium ampeloprasum var. porrum)
    Bernaert, Nathalie
    De Loose, Marc
    Van Bockstaele, Erik
    Van Droogenbroeck, Bart
    JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2014, 94 (06) : 1168 - 1174
  • [26] Incorporation of leek powder (Allium ampeloprasum var. porrum) in wheat bread: Technological implications, shelf life and sensory evaluation
    Bernaert, Nathalie
    Debonne, Els
    De Leyn, Ingrid
    Van Droogenbroeck, Bart
    Van Bockstaele, Filip
    LWT-FOOD SCIENCE AND TECHNOLOGY, 2022, 153
  • [27] Allium ampeloprasum var. Porrum (Alliaceae) Improves Metabolic and Reproductive Disorders Associated with Polycystic Ovary Syndrome in Wistar Rats
    Fofie Tedongmo, Alison Degrace
    Mvondo, Marie Alfrede
    BIOCHEMISTRY RESEARCH INTERNATIONAL, 2024, 2024
  • [28] THE ANTIOXIDANT PROPERTIES AND FATTY ACIDS PROFILE IN ORGANIC SAMPLES OF LEEKS (ALLIUM AMPELOPRASUM VAR. PORRUM) AND GARLIC (ALLIUM SATIVUM L.) IN NATURA
    Guizellini, Gloria Maria
    Sampaio, Rodrigues Geni
    da Silva, Pereira Cintia
    Manolio Soares Freitas, Rosana Aparecida
    Ferraz da Silva Torres, Elizabeth Aparecida
    ANNALS OF NUTRITION AND METABOLISM, 2017, 71 : 1198 - 1199
  • [29] A new steroidal saponin from the seeds of Allium tuberosum
    Hu, Guohua
    Mao, Rengang
    Ma, Zhengzhi
    FOOD CHEMISTRY, 2009, 113 (04) : 1066 - 1068
  • [30] Effect of environment fluctuations on biomass and allicin level in Allium sativum (cv. Harnas, Arkus) and Allium ampeloprasum var. ampeloprasum (GHG-L)
    Tchorzewska, Dorota
    Bocianowski, Jan
    Najda, Agnieszka
    Dabrowska, Agnieszka
    Winiarczyk, Krystyna
    JOURNAL OF APPLIED BOTANY AND FOOD QUALITY, 2017, 90 : 106 - +
12345