Adaptation by Type III CRISPR-Cas Systems: Breakthrough Findings and Open Questions

被引：5
|
作者：
Zhang, Xinfu [1 ,2 ]
An, Xinmin [2 ]
机构：
[1] Univ Georgia, Dept Biochem & Mol Biol, Athens, GA 30602 USA
[2] Beijing Forestry Univ, Coll Biol Sci & Technol, Beijing Adv Innovat Ctr Tree Breeding Mol Design, Natl Engn Res Ctr Tree Breeding & Ecol Remediat, Beijing, Peoples R China
来源：
FRONTIERS IN MICROBIOLOGY | 2022年 / 13卷
基金：
中国国家自然科学基金;
关键词：
CRISPR-Cas system; type III; adaptation; ssDNA secondary structure; reverse transcriptase; ROLLING-CIRCLE REPLICATION; SPACER ACQUISITION; STRUCTURAL BASIS; EVOLUTIONARY CLASSIFICATION; IMMUNE-SYSTEM; RNA CLEAVAGE; FOREIGN DNA; HOST FACTOR; INTEGRATION; DEFENSE;
D O I：
10.3389/fmicb.2022.876174
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
CRISPR-Cas systems acquire heritable defense memory against invading nucleic acids through adaptation. Type III CRISPR-Cas systems have unique and intriguing features of defense and are important in method development for Genetics research. We started to understand the common and unique properties of type III CRISPR-Cas adaptation in recent years. This review summarizes our knowledge regarding CRISPR-Cas adaptation with the emphasis on type III systems and discusses open questions for type III adaptation studies.
引用
收藏
页数：9
相关论文
共 50 条
  • [41] New CRISPR-Cas systems discovered
    Hui Yang
    Dinshaw J Patel
    [J]. Cell Research, 2017, 27 : 313 - 314
  • [42] The structural biology of CRISPR-Cas systems
    Jiang, Fuguo
    Doudna, Jennifer A.
    [J]. CURRENT OPINION IN STRUCTURAL BIOLOGY, 2015, 30 : 100 - 111
  • [43] CRISPR-Cas Systems Reduced to a Minimum
    Almendros, Cristobal
    Kieper, Sebastian N.
    Brouns, Stan J. J.
    [J]. MOLECULAR CELL, 2019, 73 (04) : 641 - 642
  • [44] CRISPR-Cas systems in Proteus mirabilis
    Fallah, Mahnaz Shafaei
    Mohebbi, Alireza
    Yasaghi, Mohammad
    Ghaemi, Ezzat Allah
    [J]. INFECTION GENETICS AND EVOLUTION, 2021, 92
  • [45] Application of CRISPR-Cas systems in neuroscience
    Bonnerjee, Deepro
    Bagh, Sangram
    [J]. ADVANCES IN CRISPR/CAS AND RELATED TECHNOLOGIES, 2021, 178 : 231 - 264
  • [46] Origins and evolution of CRISPR-Cas systems
    Koonin, Eugene, V
    Makarova, Kira S.
    [J]. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2019, 374 (1772)
  • [47] Mechanisms regulating the CRISPR-Cas systems
    Zakrzewska, Marta
    Burmistrz, Michal
    [J]. FRONTIERS IN MICROBIOLOGY, 2023, 14
  • [48] CRISPR-Cas systems in multicellular cyanobacteria
    Hou, Shengwei
    Brenes-Alvarez, Manuel
    Reimann, Viktoria
    Alkhnbashi, Omer S.
    Backofen, Rolf
    Muro-Pastor, Alicia M.
    Hess, Wolfgang R.
    [J]. RNA BIOLOGY, 2019, 16 (04) : 518 - 529
  • [49] Evolution and classification of the CRISPR-Cas systems
    Makarova, Kira S.
    Haft, Daniel H.
    Barrangou, Rodolphe
    Brouns, Stan J. J.
    Charpentier, Emmanuelle
    Horvath, Philippe
    Moineau, Sylvain
    Mojica, Francisco J. M.
    Wolf, Yuri I.
    Yakunin, Alexander F.
    van der Oost, John
    Koonin, Eugene V.
    [J]. NATURE REVIEWS MICROBIOLOGY, 2011, 9 (06) : 467 - 477
  • [50] Using CRISPR-Cas systems as antimicrobials
    Bikard, David
    Barrangou, Rodolphe
    [J]. CURRENT OPINION IN MICROBIOLOGY, 2017, 37 : 155 - 160
12345