Hematopoietic stem cell transplantation for multiple sclerosis: finding equipoise

被引:6
|
作者
Burt, RK
Kozak, T
机构
[1] Northwestern Univ, Med Ctr, Chicago, IL 60611 USA
[2] Univ Hosp Kralovske Vinohrady, Dept Clin Haematol, Prague, Czech Republic
关键词
multiple sclerosis; hematopoietic stem cell transplantation;
D O I
10.1038/sj.bmt.1703942
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Hematopoietic stem cell transplantation of multiple sclerosis is rapidly expanding. Success for this approach requires an understanding of the pathophysiology of multiple sclerosis and design of trials that select patients with active inflammatory disease, low disability scores, and avoidance of conditioning agents that may damage neural stem cell compartments or further compromise already injured axons.
引用
收藏
页码:S45 / S48
页数:4
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