Three-component reaction between alkyl isocyanides, dialkyl acetylenedicarboxylates, and carboxylic acids

被引：1

作者：

Hassanabadi, Alireza ^{[1
]}

Mosslemin, Mohammad H. ^{[2
]}

Singh, Sonia ^{[2
]}

Shaterchi, Seyyed Ali ^{[2
]}

机构：

[1] Islamic Azad Univ, Zahedan Branch, Dept Chem, Zahedan, Iran

[2] Islamic Azad Univ, Yazd Branch, Dept Chem, Yazd, Iran

来源：

JOURNAL OF CHEMICAL RESEARCH | 2011年 / 11期

关键词：

multicomponent reaction; alkyl isocyanide; dialkyl acetylene dicarboxylate; carboxylic acids; MULTICOMPONENT REACTIONS; DIMETHYL ACETYLENEDICARBOXYLATE; 4-COMPONENT REACTION; PASSERINI-REACTION;

D O I：

10.3184/174751911X13202454406382

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Protonation of the reactive intermediates produced in the reaction between alkyl isocyanides and dialkyl acetylenedicarboxylates by carboxylic acids leads to vinylnitrilium cations which then undergo nucleophilic addition of the conjugate bases of the carboxylic acids. This intermediate rearranges to produce dialkyl (E)2-{[(aryl) acetyl(alkylamino)]carbonyl}-2-butenedioate derivatives.

引用

页码：661 / 663

页数：3

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