An MR Compatible LSO-PET Scanner for Molecular Imaging Studies

被引:0
|
作者
Mackewn, J. E. [1 ]
Keevil, S. F.
Hallett, W. A. [1 ,2 ]
Halsted, P. [1 ]
Page, R. A. [1 ]
Kelly, M.
Williams, S. C. R. [3 ]
Marsden, P. K. [1 ]
机构
[1] Kings Coll London, Guys Kings & St Thomas Sch Med, London, England
[2] GlaxoSmithKline, Translat Med & Technol, Greenford, Middx, England
[3] Kings Coll London, Inst Psychiat, London, England
基金
英国工程与自然科学研究理事会;
关键词
D O I
暂无
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
We present a detailed system description of an MR compatible PET scanner for small animal molecular imaging studies, which has recently been constructed. The system images a single slice and has an inner diameter 7.5cm. It consists of 4 concentric rings of 104 LSO crystals each with nominal dimensions of 2mm (tangential) by 3mm (axial) by 5mm (radial). The crystal ring is positioned at the centre of an MR scanner, and 3.5m long optical fibres transport the scintillation light to eight multi-channel PM tubes situated in a low field region in which they can function correctly. Position encoding boards convert the large number of signals from these multichannel photo-multiplier tubes to four position encoded signals. The electronics are standard NIM modules and can be housed in just two racks, to allow the system to be relocated easily for operation in a range of MR scanners. The signals are digitized on ADC cards in a PC and the raw data converted into a sinogram using an interpolation method prior to reconstruction. We present some preliminary results from the PET system. The system will now be fully evaluated and its performance assessed within the MR environment.
引用
收藏
页码:2986 / 2989
页数:4
相关论文
共 50 条
  • [41] First experimental results of time-of-flight reconstruction on an LSO PET scanner
    Conti, M
    Bendriem, B
    Casey, M
    Chen, M
    Kehren, F
    Michel, C
    Panin, V
    PHYSICS IN MEDICINE AND BIOLOGY, 2005, 50 (19): : 4507 - 4526
  • [42] A count rate model for PET and its application to an LSO HR PLUS scanner
    Moisan, C
    Rogers, JG
    Douglas, JL
    IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1997, 44 (03) : 1219 - 1224
  • [43] Molecular imaging studies in rodents with PET
    Innis, BR
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2006, 100 : 58P - 58P
  • [44] MRI-Assisted PET Motion Correction for Neurologic Studies in an Integrated MR-PET Scanner
    Catana, Ciprian
    Benner, Thomas
    van der Kouwe, Andre
    Byars, Larry
    Hamm, Michael
    Chonde, Daniel B.
    Michel, Christian J.
    El Fakhri, Georges
    Schmand, Matthias
    Sorensen, Gregory
    JOURNAL OF NUCLEAR MEDICINE, 2011, 52 (01) : 154 - 161
  • [45] Multimodality Brain Tumor Imaging: MR Imaging, PET, and PET/MR Imaging
    Fink, James R.
    Muzi, Mark
    Peck, Melinda
    Krohn, Kenneth A.
    JOURNAL OF NUCLEAR MEDICINE, 2015, 56 (10) : 1554 - 1561
  • [46] Correction to: Performance Evaluation of a Newly Developed MR-Compatible Mobile PET Scanner with Two Detector Layouts
    Masao Watanabe
    Yuji Nakamoto
    Ryusuke Nakamoto
    Takayoshi Ishimori
    Tsuneo Saga
    Kaori Togashi
    Molecular Imaging and Biology, 2020, 22 : 416 - 416
  • [47] Rat thyroid gland imaging with 124I using semiconductor PET scanner and PET-MR
    Kanai, Yasukazu
    Takahashi, Naruto
    Watabe, Tadashi
    Watabe, Hiroshi
    Yamamoto, Seiichi
    Shimosegawa, Eku
    Shinohara, Atsushi
    Nakai, Kozi
    Hatazawa, Jun
    JOURNAL OF NUCLEAR MEDICINE, 2012, 53
  • [48] A MR Compatible PET Insert for Human Neuro Imaging: Optimization and Initial Human Study
    Jung, Jiwoong
    Choi, Yong
    Jung, Jin Ho
    Kim, Sangsu
    Im, Ki Chun
    Park, Hyun Wook
    Cho, Gyuseong
    2015 IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE (NSS/MIC), 2015,
  • [49] Magnet-safe is not the same as magnet compatible in the MR scanner
    Keens, SJ
    Laurence, AS
    ANAESTHESIA, 2004, 59 (05) : 516 - 517
  • [50] PET Performance Evaluation of an MR-Compatible PET Insert
    Wu, Yibao
    Catana, Ciprian
    Farrell, Richard
    Dokhale, Purushottam A.
    Shah, Kanai S.
    Qi, Jinyi
    Cherry, Simon R.
    IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2009, 56 (03) : 574 - 580