Chemical Constituents from Scindapsus officinalis (Roxb.) Schott. and Their Anti-Inflammatory Activities

被引：5

作者：

Dong, Hongjing ^{[1
]}

Geng, Yanling ^{[1
]}

Wang, Xueyong ^{[2
]}

Song, Xiangyun ^{[1
]}

Wang, Xiao ^{[1
]}

Yu, Jinqian ^{[1
]}

机构：

[1] Qilu Univ Technol, Shandong Acad Sci, Shandong Anal & Test Ctr, Shandong Key Lab TCM Qual Control Technol, Jinan 250014, Shandong, Peoples R China

[2] Beijing Univ Chinese Med, Coll Chinese Mareria Med, Beijing 100102, Peoples R China

来源：

MOLECULES | 2018年 / 23卷 / 10期

关键词：

Scindapsus officinalis; monoterpene glycoside; phenyl glycoside; caffeoyl derivative; anti-inflammatory activity;

D O I：

10.3390/molecules23102577

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

One new monoterpene glycoside (1), one new phenyl glycoside (2), one new caffeoyl derivative (3), were isolated from Scindapsus officinalis (Roxb.) Schott., along with four known compounds (4-7). Structures of the isolated compounds were elucidated by extensive analysis of spectroscopic data, especially 2D NMR data and comparison with literatures. All isolates were evaluated for anti-inflammatory activity against nitric oxide (NO) production in vitro. Compounds 3 and 7 exhibited moderate inhibitory effects on NO production with IC50 values of 12.2 +/- 0.8 and 18.9 +/- 0.3 mu M, respectively.

引用

页数：10

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