Integrated CT-SPECT system for small animal imaging

被引：17

作者：

Williams, MB ^{[1
]}

Zhang, GM ^{[1
]}

More, MJ ^{[1
]}

Goode, AR ^{[1
]}

Majewski, S ^{[1
]}

Wojcik, R ^{[1
]}

Kross, B ^{[1
]}

Popov, V ^{[1
]}

Weisenberger, AG ^{[1
]}

Stanton, M ^{[1
]}

Phillips, W ^{[1
]}

Stewart, A ^{[1
]}

McCauley, T ^{[1
]}

Wu, T ^{[1
]}

DiBella, EVR ^{[1
]}

机构：

[1] Univ Virginia, Dept Radiol, Charlottesville, VA 22908 USA

来源：

PENETRATING RADIATION SYSTEMS AND APPLICATIONS II | 2000年 / 4142卷

关键词：

imaging; tomography; small animal; SPECT; CT; dual modality;

D O I：

10.1117/12.410571

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

We are developing a scanner for simultaneous acquisition of x-ray computed tomography (CT) and single photon emission tomography (SPECT) images of small animals such as mice and rats. The scanner uses a cone beam geometry for both the xray transmission and gamma emission projections by using an area x-ray detector and pinhole collimator, respectively, The CT and SPECT data sets are overlaid to form a coregistered structural-functional 3D image. The CT system includes a single CCD-based x-ray detector and a microfocus x-ray source. The SPECT scanner utilizes tungsten pinhole collimators and arrays of CsI(T1) scintillation detectors. We describe design considerations and the early performance of a prototype scanner.

引用

页码：265 / 274

页数：4

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