Cellulose sulfuric acid as a bio-supported and recyclable solid acid catalyst for the one-pot three-component synthesis of α-amino nitriles

被引:125
|
作者
Shaabani, Ahmad [1 ]
Maleki, Ali [1 ]
机构
[1] Shahid Beheshti Univ Med Sci, Dept Chem, Tehran 4716, Iran
关键词
cellulose sulfuric acid; Bio-supported catalyst; a-Amino nitrites; Trimethylsilyicyanide; Multi-component reaction;
D O I
10.1016/j.apcata.2007.07.021
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
alpha-Amino nitriles are synthesized by a one-pot three-component condensation reaction of amines, aldehydes and trimethylsilylcyanide in the presence of a catalytic amount of cellulose sulfuric acid as a bio-supported catalyst, in excellent yields with short reaction times at ambient temperature. The reaction work-up is simple and the catalyst can be easily separated from the product and reused in subsequent reactions. (C) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:149 / 151
页数:3
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