Synthesis, structure and anticancer studies of Cu( II ) and Ni( II ) complexes based on 2-hydroxy-1-naphthaldehyde-4-aminoantipyrine Schiff-base

被引：6

作者：

Qi, Jiajia ^{[1
]}

Luo, Yun ^{[1
]}

Zhou, Qianxi ^{[1
]}

Su, Guozhen ^{[1
]}

Zhang, Xuan ^{[1
]}

Nie, Xuegang ^{[1
]}

Lv, Mingyue ^{[1
]}

Li, Wenge ^{[1
]}

机构：

[1] Bengbu Med Coll, Dept Chem, Bengbu 233030, Peoples R China

来源：

JOURNAL OF MOLECULAR STRUCTURE | 2022年 / 1255卷

关键词：

Schiff-base; Nickel complex; Copper complex; Crystal structure; Cytoxicity studies; METAL-COMPLEXES; HETEROCYCLIC-COMPOUNDS; CHEMISTRY; DNA;

D O I：

10.1016/j.molstruc.2022.132458

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Two metal-organic complexes of [CuLCl] (1), and [Ni2L2(C2H5OH)(2)Cl-2]center dot 2(C2H5OH)(2)(2) (HL= 2-hydroxy-1-naphthaldehyde-4-aminoantipyrine) were solvothermally synthesized from Schiff-base ligands. Single-crystal X-ray diffraction analysis shows that the mononuclear complex 1 is monoclinic while the dinuclear complex 2 belongs to triclinic crystal structure and the two complexes are both monomer molecules. Additionally, the cancer cytotoxicity, cell migration, and apoptosis properties of both complexes have been investigated. Owing to different coordination behavior between Ni(II) and Cu(II), it was found that com-plex 1 obviously displayed cytotoxicity and decreased cell migration rate by inducing apoptosis of SMMC-7721 cells (hepatoma carcinoma cells). (c) 2022 Published by Elsevier B.V.

引用

页数：12

共 50 条

[31] SCHIFF-BASE FORMATION FROM COORDINATED DIAMINE IN MIXED COMPLEXES OF CU(II) AND NI(II)
PARIKH, PC
BHATTACHARYA, PK
INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY, 1976, 14 (08): : 617 - 618
[32] CU(II), NI(II), ZN(II), CO(II) AND CD(II) COMPLEXES OF 2-HYDROXY-1-NAPHTHALDEHYDE-SEMICARBAZONE
MAYADEO, MS
KABADI, MB
VARTAK, DG
DESAI, AG
INDIAN JOURNAL OF CHEMISTRY, 1975, 13 (05): : 520 - 522
[33] MONONUCLEAR AND BINUCLEAR CO(II), NI(II) AND CU(II) CHELATES OF SCHIFF-BASE DERIVED FROM 2,6-DIAMINOPYRIDINE OR 2,6-DIAMINO-4-CHLOROPYRIMIDINE AND SALICYLALDEHYDE OR 2-HYDROXY-1-NAPHTHALDEHYDE
ALY, FA
GABER, M
ISSA, RM
ELSAIED, FA
BULLETIN DE LA SOCIETE CHIMIQUE DE FRANCE, 1988, (04): : 661 - 664
[34] SYNTHESIS AND CHARACTERIZATION OF FE(III), CO(II), NI(II) AND CU(II) COMPLEXES WITH SCHIFF-BASE OF 5-PHENYLAZOSALICYLIDENEANILINE
PUJAR, MA
BHARAMAGOUDAR, TD
JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 1980, 57 (05) : 462 - 465
[35] SYNTHESIS AND CHARACTERIZATION OF 5-COORDINATE NI(II), CU(II) AND CO(II) COMPLEXES WITH KETOIMINATO SCHIFF-BASE LIGANDS
WILLIS, LJ
CHU, DE
MCKINNEY, BD
CUMMINGS, SC
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1978, 175 (MAR): : 13 - 13
[36] Schiff base derived from 2-hydroxy-1-naphthaldehyde and liquid-assisted mechanochemical synthesis of its isostructural Cu(II) and Co(II) complexes
Cincic, Dominik
Kaitner, Branko
CRYSTENGCOMM, 2011, 13 (13): : 4351 - 4357
[37] Synthesis and Spectral Studies of Zinc (II) Complexes of a Schiff Base Derived from Isatin Hydrazone and 2-Hydroxy Naphthaldehyde
Renjitha, J.
Thara, G. S.
LET THERE BE LIGHT: REFLECTIONS OF A CONGRESS ON LIGHT, 2017, 1849
[38] Template synthesis and structure of Co(II), Ni(II), and Cu(II) complexes with pyridoxilydenetaurinate Schiff base ligand
Guricova, Miroslava
Pizl, Martin
Smekal, Zdenek
Nadherny, Ladislav
Cejka, Jan
Eigner, Vaclav
Hoskovcova, Irena
INORGANICA CHIMICA ACTA, 2018, 477 : 248 - 256
[39] CU(II) AND NI(II) COMPLEXES WITH A TETRADENTATE SCHIFF-BASE DERIVED FROM 2-HYDROXYNAPHTHALDEHYDE AND ETHYLENEDIAMINE
AHMED, I
AKHTAR, F
INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY, 1981, 20 (07): : 737 - 738
[40] Synthesis, spectroscopic investigation and antimicrobial studies on some schiff base complexes of Cu(II) and Ni(II)
Ajith Sinthuja, S.
Sudha Kumari, S.
Journal of Chemical and Pharmaceutical Research, 2013, 5 (05) : 303 - 309

← 1 2 3 4 5 →