Nickel-Catalyzed Stereoselective Arylboration of Unactivated Alkenes

被引：101
|
作者：
Logan, Kaitlyn M. [1 ]
Sardini, Stephen R. [1 ]
White, Sean D. [1 ]
Brown, M. Kevin [1 ]
机构：
[1] Indiana Univ, Dept Chem, 800 East Kirkwood Ave, Bloomington, IN 47405 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2018年 / 140卷 / 01期
关键词：
CROSS-COUPLING REACTIONS; BORYLATIVE EXO-CYCLIZATION; ENANTIOSELECTIVE ARYLBORATION; COPPER(I)-CATALYZED REACTION; REGIOSELECTIVE ARYLBORATION; 3-COMPONENT CARBOBORATION; ORGANOMETALLIC REAGENTS; COOPERATIVE CATALYSIS; SYNERGISTIC CATALYSIS; ASYMMETRIC-SYNTHESIS;
D O I：
10.1021/jacs.7b12160
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A Ni-catalyzed method for arylboration is disclosed. The method allows for highly stereoselective arylboration of unactivated alkenes. The reactions utilize a simple Ni-catalyst and work with a broad range of alkenes and aryl bromides. The products represent useful intermediates for chemical synthesis due to the versatility of the C-B bond. Preliminary mechanistic details of the method are also disclosed.
引用
收藏
页码：159 / 162
页数：4
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