Use of Quantitative HIV RNA Detection for Early Diagnosis of HIV Infection in Infants and Acute HIV Infections in Alberta, Canada

被引：10
|
作者：
Lee, Bonita E. [1 ]
Plitt, Sabrina S. [2 ]
Jayaraman, Gayatri C. [3 ]
Chui, Linda [4 ,5 ]
Singh, Ameeta E. [6 ]
Preiksaitis, Jutta K. [6 ]
机构：
[1] Univ Alberta, Dept Pediat, Edmonton, AB, Canada
[2] Publ Hlth Agcy Canada, Ottawa, ON, Canada
[3] Univ Calgary, Dept Community Hlth Sci, Calgary, AB, Canada
[4] Prov Lab Publ Hlth, Edmonton, AB, Canada
[5] Univ Alberta, Dept Lab Med & Pathol, Edmonton, AB, Canada
[6] Univ Alberta, Dept Med, Edmonton, AB, Canada
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2012年 / 50卷 / 02期
关键词：
VIRUS; IDENTIFICATION; ASSAYS;
D O I：
10.1128/JCM.05471-11
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Quantitative HIV RNA viral load (QVL) assays (Roche Diagnostics) were sensitive and specific when used to diagnose HIV infection in (i) HIV-exposed infants (sensitivity of 100% [63.1 to 100%] and specificity of 100% [97.9 to 100%]) and (ii) suspected acute HIV infection patients with a negative/indeterminate Western blot (sensitivity of 97.6% [91.6 to 99.7%] and specificity of 100% [96.1 to 100%]). No false-positive QVL results were identified.
引用
收藏
页码：502 / 505
页数：4
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