A Novel Biodegradable Multichamber Microstructure for Implantable drug Controlled Release

被引：0
|
作者：
Yu, Ruixia [1 ]
ZHou, XiangYang [2 ]
Zhao, Zeng [1 ]
机构：
[1] Univ Sci & Technol Beijing, Sch Mech Engn, Beijing 100083, Peoples R China
[2] Beijing Univ Aeronaut & Astronaut, Sch Instrumentat Sci & Optoelect Engn, Beijing, Peoples R China
来源：
PRICM 7, PTS 1-3 | 2010年 / 654-656卷
关键词：
Biodegradable polymer; Topology optimization; drug controlled release; UV-LIGA; DELIVERY;
D O I：
10.4028/www.scientific.net/MSF.654-656.2269
中图分类号：
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
The research work reported in this paper design a novel biodegradable multichamber microstructure for implantable drug controlled release by introducing the approach of topology optimization. It is therefore highly desirable to overcome these restrictions that pre-defined topology of the device result in difficulty to obtain a linear or pulsed drug release profile. The designed biodegradable multichamber microstructure is fabricated using UV-LIGA microfabrication and Micro-molding technique. The simulation results show that the multichamber microstructure exhibits a preferable linear drug release profile.
引用
收藏
页码：2269 / +
页数：2
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