Acyl flavone and lignan glucosides from Leontopodium leontopodioides

被引：20
|
作者：
Xiao, Yangyang [1 ,3 ]
Xie, Haihui [1 ]
Zhao, Li [2 ]
Gou, Ping [2 ]
机构：
[1] Chinese Acad Sci, South China Bot Garden, Key Lab South China Agr Plant Mol Anal & Genet Im, Guangzhou 510650, Guangdong, Peoples R China
[2] Xinjiang Univ, Coll Life Sci & Technol, Urumqi 830046, Peoples R China
[3] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
来源：
PHYTOCHEMISTRY LETTERS | 2016年 / 17卷
基金：
中国国家自然科学基金;
关键词：
Leontopodium leontopodioides; Acyl flavone glucoside; Acyl lignan glucoside; alpha-Glucosidase inhibition; PHENOLICS; SAPONINS;
D O I：
10.1016/j.phytol.2016.08.006
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new acyl flavone glucosides, luteolin-4 '-O-(6-p-hydroxybenzoyl)-beta-D-glucopyranoside (leontopodioside A, 1) and luteolin-4 '-O-[ 6-(2-methylbutyryl)]-beta-D-glucopyranoside (leontopodioside B, 2), and a new acyl lignan glucoside, lariciresinol-9-angeloyl-4-O-beta-D-glucopyranoside (leontopodioside C, 3) were isolated from the whole plants of Leontopodium leontopodioides (Asteraceae). Their structures were determined by spectroscopic and chemical methods. Compounds 1-3 exhibited alpha-glucosidase inhibitory activity with the half maximal inhibitory concentration (IC50) values of 55.6, 39.7, and 474.9 mu M, respectively, in comparison with acarbose (626.3 mu M). (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：247 / 250
页数：4
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