Palladium-Catalyzed Oxidative Borylation of Allylic C-H Bonds in Alkenes

被引：31

作者：

Mao, Lujia ^{[1
,2
]}

Bertermann, Ruediger ^{[1
,2
]}

Rachor, Simon G. ^{[1
,2
]}

Szabo, Kalman J. ^{[3
]}

Marder, Todd B. ^{[1
,2
]}

机构：

[1] Julius Maximilians Univ Wurzburg, Inst Anorgan Chem, D-97074 Wurzburg, Germany

[2] Julius Maximilians Univ Wurzburg, Inst Sustainable Chem & Catalysis Boron, D-97074 Wurzburg, Germany

[3] Stockholm Univ, Dept Organ Chem, Arrhenius Lab, SE-10691 Stockholm, Sweden

来源：

ORGANIC LETTERS | 2017年 / 19卷 / 24期

基金：

瑞典研究理事会;

关键词：

ALKOXY DIBORON REAGENTS; ARYL HALIDES; REDUCTIVE ELIMINATION; ROOM-TEMPERATURE; EFFICIENT ROUTE; ALKYL-HALIDES; COMPLEX; FUNCTIONALIZATION; SUBSTITUTION; ACTIVATION;

D O I：

10.1021/acs.orglett.7b03296

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This communication describes an efficient palladium pincer complex-catalyzed allylic C-H borylation of alkenes. The transformation exhibits high regio- and stereo selectivity with a variety of linear alkenes. A synthetically useful feature of this allylic C-H borylation method is that all allyl-Bpin products can be isolated in usually high yields. Preliminary mechanistic studies indicate that this CH borylation reaction proceeds via Pd(IV) pincer complex intermediates.

引用

页码：6590 / 6593

页数：4

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