Palladium-Catalyzed Oxidative Allylic C-H Silylation

被引：58
|
作者：
Larsson, Johanna M. [1 ]
Zhao, Tony S. N. [1 ]
Szabo, Kalmin J. [1 ]
机构：
[1] Stockholm Univ, Arrhenius Lab, Dept Organ Chem, SE-10691 Stockholm, Sweden
来源：
ORGANIC LETTERS | 2011年 / 13卷 / 07期
基金：
瑞典研究理事会;
关键词：
DIRECT ARYLATION; BOND FORMATION; DEHYDROGENATIVE BORYLATION; ORGANIC-MOLECULES; CYCLIC ALKENES; COMPLEXES; FUNCTIONALIZATION; ACTIVATION; CHEMISTRY; MECHANISM;
D O I：
10.1021/ol200445b
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Palladium-catalyzed allylic C-H silylation was performed with use of hexamethyldisilane as the silyl source. These C-H functionalization reactions occur only in the presence of hypervalent iodine reagents or other strong oxidants and proceed with excellent regioselectivity, providing the linear allylic isomer of the allylsilane products. In demonstrating the first oxidative allylic C-H silylation of alkenes, this study marks an important advance for the catalytic C-H functionalization method.
引用
收藏
页码：1888 / 1891
页数：4
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