Nuclear Imaging of Neuroendocrine Tumors

被引：11
|
作者：
Pollard, Janet [1 ]
McNeely, Parren [1 ]
Menda, Yusuf [1 ]
机构：
[1] Univ Iowa Hosp & Clin, Roy J & Lucille A Carver Coll Med, Dept Radiol, 200 Hawkins Dr, Iowa City, IA 52242 USA
来源：
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2020年 / 29卷 / 02期
关键词：
Nuclear imaging; Neuroendocrine tumors; NET; Somatostatin receptor analog; Gallium Ga-68; EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY; ENETS CONSENSUS GUIDELINES; GA-68-DOTATATE PET/CT; LIVER METASTASES; CLINICAL UTILITY; MANAGEMENT; NEOPLASMS; PET/MRI; MIDGUT; DOSIMETRY;
D O I：
10.1016/j.soc.2019.11.007
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Consensus guidelines acknowledge the role of gallium Ga-68 (Ga-68) 1,4,7,10-tetraazacyclododecane-N,N',N '',N'''-tetraacetic (DOTA) somatostatin receptor (SSTR) positron emission tomography/computed tomography (PET/CT) in management of neuroendocrine tumor (NET) patients. Ga-68-DOTA-SSTR PET/CT demonstrates superior performance to conventional imaging in initial detection, staging, detection of recurrent tumor, and detection of unknown primary in known metastatic disease. Ga-68-DOTA-SSTR PET/CT is low yield for NET detection in the setting of symptoms or elevated biomarkers when conventional imaging is negative, but may still guide management. The role of Ga-68-DOTA-SSTR PET/CT is not established in monitoring response to systemic therapy but may identify progression through detection of new metastases.
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页码：209 / +
页数：14
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