Nuclear Imaging of Neuroendocrine Tumors

被引：11

作者：

Pollard, Janet ^{[1
]}

McNeely, Parren ^{[1
]}

Menda, Yusuf ^{[1
]}

机构：

[1] Univ Iowa Hosp & Clin, Roy J & Lucille A Carver Coll Med, Dept Radiol, 200 Hawkins Dr, Iowa City, IA 52242 USA

来源：

SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2020年 / 29卷 / 02期

关键词：

Nuclear imaging; Neuroendocrine tumors; NET; Somatostatin receptor analog; Gallium Ga-68; EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY; ENETS CONSENSUS GUIDELINES; GA-68-DOTATATE PET/CT; LIVER METASTASES; CLINICAL UTILITY; MANAGEMENT; NEOPLASMS; PET/MRI; MIDGUT; DOSIMETRY;

D O I：

10.1016/j.soc.2019.11.007

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Consensus guidelines acknowledge the role of gallium Ga-68 (Ga-68) 1,4,7,10-tetraazacyclododecane-N,N',N '',N'''-tetraacetic (DOTA) somatostatin receptor (SSTR) positron emission tomography/computed tomography (PET/CT) in management of neuroendocrine tumor (NET) patients. Ga-68-DOTA-SSTR PET/CT demonstrates superior performance to conventional imaging in initial detection, staging, detection of recurrent tumor, and detection of unknown primary in known metastatic disease. Ga-68-DOTA-SSTR PET/CT is low yield for NET detection in the setting of symptoms or elevated biomarkers when conventional imaging is negative, but may still guide management. The role of Ga-68-DOTA-SSTR PET/CT is not established in monitoring response to systemic therapy but may identify progression through detection of new metastases.

引用

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页码：209 / +

页数：14

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