The coexpression of CD5 and CD10 has previously been reported in cases of intermediate- and high-grade lymphomas and in precursor B cells in normal or regenerating bone marrow. We report 3 cases of low-grade B-cell lymphoma that were found to coexpress CD5 and CD10 at the time of initial diagnosis. The first case was classified as small lymphocytic lymphoma; the second as follicle center lymphoma, follicular grade 1; and the third as small B-cell lymphoma otherwise not specified. Currently, the clinical implication of the coexpression of CD5 and CD10 is not known. We describe this finding to highlight the difficulty that may he encountered in classifying lymphomas in cases where this coexpression is present.
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Columbia Univ, Coll Phys & Surg, Columbia Presbyterian Med Ctr, Dept Pathol, New York, NY USAColumbia Univ, Coll Phys & Surg, Columbia Presbyterian Med Ctr, Dept Pathol, New York, NY USA
Ballesteros, E
Osborne, BM
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Columbia Univ, Coll Phys & Surg, Columbia Presbyterian Med Ctr, Dept Pathol, New York, NY USAColumbia Univ, Coll Phys & Surg, Columbia Presbyterian Med Ctr, Dept Pathol, New York, NY USA
Osborne, BM
Matsushima, AY
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Columbia Univ, Coll Phys & Surg, Columbia Presbyterian Med Ctr, Dept Pathol, New York, NY USAColumbia Univ, Coll Phys & Surg, Columbia Presbyterian Med Ctr, Dept Pathol, New York, NY USA
机构:
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-3135Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-3135
Schneider A.
Meyer P.
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Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-3135Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-3135
Meyer P.
DiMaio D.
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Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-3135Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-3135
DiMaio D.
Fu K.
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Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-3135Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198-3135