The coexpression of CD5 and CD10 has previously been reported in cases of intermediate- and high-grade lymphomas and in precursor B cells in normal or regenerating bone marrow. We report 3 cases of low-grade B-cell lymphoma that were found to coexpress CD5 and CD10 at the time of initial diagnosis. The first case was classified as small lymphocytic lymphoma; the second as follicle center lymphoma, follicular grade 1; and the third as small B-cell lymphoma otherwise not specified. Currently, the clinical implication of the coexpression of CD5 and CD10 is not known. We describe this finding to highlight the difficulty that may he encountered in classifying lymphomas in cases where this coexpression is present.
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Mayo Clin, Div Hematopathol, Dept Lab Med & Pathol, Rochester, MN 55905 USAMayo Clin, Div Hematopathol, Dept Lab Med & Pathol, Rochester, MN 55905 USA
Morice, WG
Hodnefield, JM
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Mayo Clin, Div Hematopathol, Dept Lab Med & Pathol, Rochester, MN 55905 USAMayo Clin, Div Hematopathol, Dept Lab Med & Pathol, Rochester, MN 55905 USA
Hodnefield, JM
Kurtin, PJ
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Mayo Clin, Div Hematopathol, Dept Lab Med & Pathol, Rochester, MN 55905 USAMayo Clin, Div Hematopathol, Dept Lab Med & Pathol, Rochester, MN 55905 USA
Kurtin, PJ
Hanson, CA
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Mayo Clin, Div Hematopathol, Dept Lab Med & Pathol, Rochester, MN 55905 USAMayo Clin, Div Hematopathol, Dept Lab Med & Pathol, Rochester, MN 55905 USA