Tyrosinase Inhibitors from the Stems of Streblus Ilicifolius

被引：3
|
作者：
Nguyen, Nhan T. [1 ,2 ,3 ]
Dang, Phu H. [1 ,2 ]
Nguyen, Hai X. [1 ,2 ]
Do, Truong N., V [1 ,2 ]
Le, Tho H. [1 ,2 ]
Le, Tuyen Q. H. [1 ,2 ]
Nguyen, Mai T. T. [1 ,2 ,3 ]
机构：
[1] Univ Sci, Fac Chem, 227 Nguyen Van Cu St,Ward 4,Dist 5, Ho Chi Minh City, Vietnam
[2] Vietnam Natl Univ, Linh Trung Ward, Quarter 6, Ho Chi Minh City, Vietnam
[3] Univ Sci, Canc Res Lab, 227 Nguyen Van Cu St,Dist 5, Ho Chi Minh City, Vietnam
来源：
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2021年 / 2021卷
关键词：
D O I：
10.1155/2021/5561176
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
Two new stilbene derivatives, named strebluses C and D, were isolated from the EtOAc-soluble fraction of the stems of Streblus ilicifolius (Moraceae). Its absolute configuration was elucidated based on NMR spectroscopic data interpretation and optical rotation calculation. Streblus C possesses strong tyrosinase inhibitory activity with an IC50 value of 0.01 mu M. Docking studies of 1 and 2 with oxy-tyrosinase were carried out to analyze their interactions. The analysis of the docked poses confirmed that 1 showed better binding affinity for oxy-tyrosinase than that of 2.
引用
收藏
页数：7
相关论文
共 50 条
  • [31] TYROSINASE INHIBITORS FROM ANACARDIUM-OCCIDENTALE FRUITS
    KUBO, I
    KINSTHORI, I
    YOKOKAWA, Y
    JOURNAL OF NATURAL PRODUCTS, 1994, 57 (04): : 545 - 551
  • [32] Glabrene and isoliquiritigenin as tyrosinase inhibitors from licorice roots
    Nerya, O
    Vaya, J
    Musa, R
    Izrael, S
    Ben-Arie, R
    Tamir, S
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2003, 51 (05) : 1201 - 1207
  • [33] Natural tyrosinase inhibitors from Betula platyphylla barks
    Shu, Peng-Hua
    Zhang, Hui
    Li, Nian-Ci
    Zhang, Jia-Long
    Liu, Guang-Wei
    Yang, Yuan
    Zang, Shuo
    Cai, Shu-Jing
    Wei, Xia-Lan
    Sun, Na
    Xiao, Fu-Gang
    HOLZFORSCHUNG, 2022, 76 (07) : 674 - 678
  • [34] Isolation of tyrosinase inhibitors from sopora fravescens.
    Ha, TJ
    Park, KH
    Lee, JR
    Kang, NS
    Lee, J
    Hwang, SW
    Yang, MS
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 223 : U39 - U39
  • [35] Characterization of Tyrosinase Inhibitors from White Lotus Receptacle
    Wu, Jing
    Xu, Jian-Guo
    Fu, Jian-Ping
    Xiong, Wei
    Zhang, Sen-Wang
    Gu, Zhen
    Wu, Lei
    Hu, Ju-Wu
    CHEMISTRY OF NATURAL COMPOUNDS, 2019, 55 (05) : 929 - 931
  • [36] Tyrosinase inhibitors from paper mulberry (Broussonetia papyrifera)
    Zheng, Zong-Ping
    Cheng, Ka-Wing
    Chao, Jianfei
    Wu, Jiajun
    Wang, Mingfu
    FOOD CHEMISTRY, 2008, 106 (02) : 529 - 535
  • [37] Discovery of Novel Tyrosinase Inhibitors From Marine Cyanobacteria
    He, Yifan
    Suyama, Takashi L.
    Kim, Hyunwoo
    Glukhov, Evgenia
    Gerwick, William H.
    FRONTIERS IN MICROBIOLOGY, 2022, 13
  • [38] TYROSINASE INHIBITORS FROM BOLIVIAN MEDICINAL-PLANTS
    KUBO, I
    YOKOKAWA, Y
    KINSTHORI, I
    JOURNAL OF NATURAL PRODUCTS-LLOYDIA, 1995, 58 (05): : 739 - 743
  • [39] Tyrosinase inhibitors isolated from the roots of Paeonia suffruticosa
    Ding, Hsiou-Yu
    Lin, Hang-Ching
    Chang, Te-Sheng
    JOURNAL OF COSMETIC SCIENCE, 2009, 60 (03) : 347 - 352
  • [40] Characterization of Tyrosinase Inhibitors from White Lotus Receptacle
    Jing Wu
    Jian-Guo Xu
    Jian-Ping Fu
    Wei Xiong
    Sen-Wang Zhang
    Zhen Gu
    Lei Wu
    Ju-Wu Hu
    Chemistry of Natural Compounds, 2019, 55 : 929 - 931
12345