Tyrosinase Inhibitors from the Stems of Streblus Ilicifolius

被引：3
|
作者：
Nguyen, Nhan T. [1 ,2 ,3 ]
Dang, Phu H. [1 ,2 ]
Nguyen, Hai X. [1 ,2 ]
Do, Truong N., V [1 ,2 ]
Le, Tho H. [1 ,2 ]
Le, Tuyen Q. H. [1 ,2 ]
Nguyen, Mai T. T. [1 ,2 ,3 ]
机构：
[1] Univ Sci, Fac Chem, 227 Nguyen Van Cu St,Ward 4,Dist 5, Ho Chi Minh City, Vietnam
[2] Vietnam Natl Univ, Linh Trung Ward, Quarter 6, Ho Chi Minh City, Vietnam
[3] Univ Sci, Canc Res Lab, 227 Nguyen Van Cu St,Dist 5, Ho Chi Minh City, Vietnam
来源：
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2021年 / 2021卷
关键词：
D O I：
10.1155/2021/5561176
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
Two new stilbene derivatives, named strebluses C and D, were isolated from the EtOAc-soluble fraction of the stems of Streblus ilicifolius (Moraceae). Its absolute configuration was elucidated based on NMR spectroscopic data interpretation and optical rotation calculation. Streblus C possesses strong tyrosinase inhibitory activity with an IC50 value of 0.01 mu M. Docking studies of 1 and 2 with oxy-tyrosinase were carried out to analyze their interactions. The analysis of the docked poses confirmed that 1 showed better binding affinity for oxy-tyrosinase than that of 2.
引用
收藏
页数：7
相关论文
共 50 条
  • [1] Strebluses E-H, four new stilbene-like derivatives from the stems of Streblus ilicifolius
    Le, Tho Huu
    Dang, Phu Hoang
    Nguyen, Hai Xuan
    Do, Truong Nhat Van
    Nguyen, Nhan Trung
    Nguyen, Mai Thanh Thi
    RSC ADVANCES, 2022, 13 (01) : 570 - 574
  • [2] Determination of Phytochemical Compounds, and Tyrosinase Inhibitory and Antimicrobial Activities of Bioactive Compounds from Streblus ilicifolius (S Vidal) Corner
    Dej-adisai, Sukanya
    Parndaeng, Kedsaraporn
    Wattanapiromsakul, Chatchai
    TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2016, 15 (03) : 497 - 506
  • [3] Phenolic tyrosinase inhibitors from the stems of Cudrania cochinchinensis
    Zheng, Zong-Ping
    Zhu, Qin
    Fan, Chun-Lin
    Tan, Hui-Yuan
    Wang, Mingfu
    FOOD & FUNCTION, 2011, 2 (05) : 259 - 264
  • [4] A new phenylpropanoid glycoside from the bark of Streblus ilicifolius (Vidal) Corner
    Zhang, Gaorong
    Hao, Lili
    Zhou, Dexiong
    Liu, Wei
    Li, Chenguo
    Su, Shanshan
    Xu, Xia
    Huang, Xishan
    Li, Jun
    BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2019, 87
  • [5] Two new derivatives of 8-prenyl-5,7-dihydroxycoumarin from the stems of Streblus ilicifolius (S.Vidal) Corn
    Nguyen, Nhan Trung
    Nguyen, Hai Xuan
    Le, Tho Huu
    Nguyen, Du Huy
    Do, Truong Nhat Van
    Dang, Phu Hoang
    Nguyen, Mai Thanh Thi
    NATURAL PRODUCT RESEARCH, 2022, 36 (19) : 4967 - 4972
  • [6] Diarylalkanoids as Potent Tyrosinase Inhibitors from the Stems of Semecarpus caudata
    Dang, Phu H.
    Le, Tho H.
    Do, Truong N. V.
    Nguyen, Hai X.
    Nguyen, Mai T. T.
    Nguyen, Nhan T.
    EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2021, 2021
  • [7] Taxotrophises A and B, two new polyphenols from the stems of Taxotrophis ilicifolius
    Van Do, Truong Nhat
    Nguyen, Hai Xuan
    Le, Tho Huu
    Dang, Phu Hoang
    Nguyen, Nhan Trung
    Nguyen, Mai Thanh Thi
    NATURAL PRODUCT RESEARCH, 2024, 38 (13) : 2187 - 2192
  • [8] Megastigmane glycosides from Streblus ilicifolius (S.Vidal) Corner and their anti-inflammatory activity
    Huang, Yan
    Pan, Liwei
    Chang, Yanling
    Liang, Xiaoqin
    Hou, Ping
    Ren, Chenyang
    Xu, Weifeng
    Yang, Ruiyun
    Li, Jun
    Liu, Buming
    PHYTOCHEMISTRY, 2023, 208
  • [9] Two new amide glycosides with anti-inflammatory activity from the leaves of Streblus ilicifolius (Vidal) Corner
    Huang, Yan
    Huang, Xishan
    Tian, Guobiao
    Zhang, Wenxiu
    Su, Shanshan
    Xu, Xia
    Li, Jun
    Liu, Buming
    NATURAL PRODUCT RESEARCH, 2022, 36 (06) : 1485 - 1493
  • [10] Tyrosinase Inhibitory Constituents from the Stems of Maackia fauriei
    Kim, Jeong Mi
    Ko, Ryeo Kyeong
    Jung, Duk Sang
    Kim, Sang Suk
    Lee, Nam Ho
    PHYTOTHERAPY RESEARCH, 2010, 24 (01) : 70 - 75
12345