Cytotoxicity evaluation of environmentally friendly synthesis Copper/Zinc bimetallic nanoparticles on MCF-7 cancer cells

被引:36
|
作者
Zadeh, Firoozeh Abolhasani [1 ]
Bokov, Dmitry Olegovich [2 ,3 ]
Salahdin, Omar Dheyauldeen [4 ]
Abdelbasset, Walid Kamal [5 ,6 ]
Jawad, Mohammed Abed [7 ]
Kadhim, Mustafa M. [8 ,9 ,10 ]
Qasim, Maytham T. [11 ]
Kzar, Hamzah H. [12 ]
Al-Gazally, Moaed E. [13 ]
Mustafa, Yasser Fakri [14 ]
Khatami, M. [15 ]
机构
[1] Kerman Univ Med Sci, Fac Med, Dept Surg, Kerman, Iran
[2] Sechenov First Moscow State Med Univ, Inst Pharm, 8 Trubetskaya St,Bldg 2, Moscow 119991, Russia
[3] Fed Res Ctr Nutr Biotechnol & Food Safety, Lab Food Chem, 2-14 Ustyinsky Pr, Moscow 109240, Russia
[4] Dept Al Maarif Univ Coll, Med Lab Tech, Anbar Ramadi, Iraq
[5] Prince Sattam Bin Abdulaziz Univ, Coll Appl Med Sci, Dept Hlth & Rehabil Sci, Al Kharj, Saudi Arabia
[6] Cairo Univ, Kasr Al Aini Hosp, Dept Phys Therapy, Giza, Egypt
[7] Al Nisour Univ Coll, Baghdad, Iraq
[8] Kut Univ Coll, Dept Dent, Kut 52001, Wasit, Iraq
[9] Islamic Univ, Coll Tech Engn, Najaf, Iraq
[10] Osol Aldeen Univ Coll, Dept Pharm, Baghdad, Iraq
[11] Al Ayen Univ, Coll Hlth & Med Technol, Dept Anesthesia, Thi Qar, Iraq
[12] Al Qasim Green Univ, Coll Vet Med, Dept Chem, Al Qasim, Iraq
[13] Univ Al Ameed, Coll Med, Karbala, Iraq
[14] Univ Mosul, Coll Pharm, Dept Pharmaceut Chem, Mosul 41001, Iraq
[15] Environm Res Ctr, Dept Environm Kerman, Kerman, Iran
关键词
Cytotoxicity; Environmentally friendly; Copper; Zinc bimetallic nanoparticle; MCF-7 cancer cells; MTT assay; GREEN SYNTHESIS; ZIRCONIA CERAMICS; CHIP THICKNESS; LUBRICATION; HEALTH; AG;
D O I
10.1007/s12210-022-01064-x
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Bimetallic nanoparticles offer unique chemical, physical and optical properties that are not available for monometallic nanoparticles. Bimetallic nanoparticles play a major role in various therapeutic, industrial and energy fields. Recently, nanoparticles of Copper/Zinc bimetallic nanoparticles have attracted attention in various fields, especially medicine. In this study, bimetallic CuO/ZnO nanostructures were biosynthesized using plant extracts. The plant-mediated synthesis nanoparticles were characterized by Transmission electron microscopy (TEM), X-ray diffraction analysis (XRD), Field Emission Scanning Electron Microscopy (FESEM) and Energy-Dispersive Spectroscopy (EDAX). The cytotoxicity of plant-mediated synthesis bimetallic nanoparticles and the synergistic effects of these nanoparticles in combination with the anticancer drug doxorubicin on MCF-7 cancer cells were evaluated by MTT assay.
引用
收藏
页码:441 / 447
页数:7
相关论文
共 50 条
  • [41] Synthesis, cytotoxicity and antitumour mechanism investigations of polyoxometalate doped silica nanospheres on breast cancer MCF-7 cells
    Cao, Hongqian
    Li, Chunyan
    Qi, Wen
    Meng, Xiangjun
    Tian, Rui
    Qi, Yanfei
    Yang, Wei
    Li, Juan
    PLOS ONE, 2017, 12 (07):
  • [42] Interaction of zinc oxide nanoparticles and nanorods with immunoglobulin G and underlying effects on MCF-7 breast cancer cells
    Chen, Keren
    Jiang, Zhuqiao
    Yu, Jingwei
    Fu, Rao
    Yin, Hui
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 305
  • [43] Synthesis of isoflavone derivatives, and the biochemical evaluation of their effect on the growth of MCF-7 breast cancer cells
    James, K. E.
    Saunders, M.
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2004, 56 : S59 - S60
  • [44] Cytotoxicity of fenugreek sprout extract and their bioactive constituents in MCF-7 breast cancer cells
    Khoja, K. K.
    Howes, M. J. R.
    Sharp, P. A.
    Latunde-Dada, G. O.
    PROCEEDINGS OF THE NUTRITION SOCIETY, 2022, 81 (OCE1)
  • [45] Development and Characterization of Chitosan-Pluronic Nanoparticles for Tamoxifen Delivery and Cytotoxicity to MCF-7 Cells
    Othayoth, Rajath
    Karthik, Varshini
    Kumar, K. Santhosh
    2013 INTERNATIONAL CONFERENCE ON ADVANCED NANOMATERIALS AND EMERGING ENGINEERING TECHNOLOGIES (ICANMEET), 2013, : 394 - 401
  • [46] Design, synthesis and antibreast cancer MCF-7 cells biological evaluation of heterocyclic analogs of resveratrol
    Du, Cheng
    Dong, Ming-Hui
    Ren, Yu-Jie
    Jin, Lu
    Xu, Cheng
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2017, 19 (09) : 890 - 902
  • [47] Cytotoxicity Enhancement in MCF-7 Breast Cancer Cells with Depolymerized Chitosan Delivery of α-Mangostin
    Herdiana, Yedi
    Wathoni, Nasrul
    Shamsuddin, Shaharum
    Muchtaridi, Muchtaridi
    POLYMERS, 2022, 14 (15)
  • [48] Efficacy of copper nanoparticles encapsulated in soya lecithin liposomes in treating breast cancer cells (MCF-7) in vitro
    Ahmed, Shaimaa A.
    Gaber, Mohamed H.
    Salama, Aida A.
    Ali, Said A.
    SCIENTIFIC REPORTS, 2023, 13 (01)
  • [49] Efficacy of copper nanoparticles encapsulated in soya lecithin liposomes in treating breast cancer cells (MCF-7) in vitro
    Shaimaa A. Ahmed
    Mohamed H. Gaber
    Aida A. Salama
    Said A. Ali
    Scientific Reports, 13
  • [50] Green synthesis, characterization, antioxidant, interaction with DNA/BSA, and investigation of cytotoxicity against MCF-7 cancer cells of zinc oxide nanoparticles using Hammada scoparia (Pomel) Iljin extract
    Benine, Chaima
    Boutlelis, Djahra Ali
    Touhami, Laiche Ammar
    Lanez, Elhafnaoui
    Amara, Djilani Ghemam
    Rim, Gatrane
    Hanen, Najjaa
    Zahnit, Wafa
    Messaoudi, Mohammed
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 295