Cytotoxicity evaluation of environmentally friendly synthesis Copper/Zinc bimetallic nanoparticles on MCF-7 cancer cells

被引:36
|
作者
Zadeh, Firoozeh Abolhasani [1 ]
Bokov, Dmitry Olegovich [2 ,3 ]
Salahdin, Omar Dheyauldeen [4 ]
Abdelbasset, Walid Kamal [5 ,6 ]
Jawad, Mohammed Abed [7 ]
Kadhim, Mustafa M. [8 ,9 ,10 ]
Qasim, Maytham T. [11 ]
Kzar, Hamzah H. [12 ]
Al-Gazally, Moaed E. [13 ]
Mustafa, Yasser Fakri [14 ]
Khatami, M. [15 ]
机构
[1] Kerman Univ Med Sci, Fac Med, Dept Surg, Kerman, Iran
[2] Sechenov First Moscow State Med Univ, Inst Pharm, 8 Trubetskaya St,Bldg 2, Moscow 119991, Russia
[3] Fed Res Ctr Nutr Biotechnol & Food Safety, Lab Food Chem, 2-14 Ustyinsky Pr, Moscow 109240, Russia
[4] Dept Al Maarif Univ Coll, Med Lab Tech, Anbar Ramadi, Iraq
[5] Prince Sattam Bin Abdulaziz Univ, Coll Appl Med Sci, Dept Hlth & Rehabil Sci, Al Kharj, Saudi Arabia
[6] Cairo Univ, Kasr Al Aini Hosp, Dept Phys Therapy, Giza, Egypt
[7] Al Nisour Univ Coll, Baghdad, Iraq
[8] Kut Univ Coll, Dept Dent, Kut 52001, Wasit, Iraq
[9] Islamic Univ, Coll Tech Engn, Najaf, Iraq
[10] Osol Aldeen Univ Coll, Dept Pharm, Baghdad, Iraq
[11] Al Ayen Univ, Coll Hlth & Med Technol, Dept Anesthesia, Thi Qar, Iraq
[12] Al Qasim Green Univ, Coll Vet Med, Dept Chem, Al Qasim, Iraq
[13] Univ Al Ameed, Coll Med, Karbala, Iraq
[14] Univ Mosul, Coll Pharm, Dept Pharmaceut Chem, Mosul 41001, Iraq
[15] Environm Res Ctr, Dept Environm Kerman, Kerman, Iran
关键词
Cytotoxicity; Environmentally friendly; Copper; Zinc bimetallic nanoparticle; MCF-7 cancer cells; MTT assay; GREEN SYNTHESIS; ZIRCONIA CERAMICS; CHIP THICKNESS; LUBRICATION; HEALTH; AG;
D O I
10.1007/s12210-022-01064-x
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Bimetallic nanoparticles offer unique chemical, physical and optical properties that are not available for monometallic nanoparticles. Bimetallic nanoparticles play a major role in various therapeutic, industrial and energy fields. Recently, nanoparticles of Copper/Zinc bimetallic nanoparticles have attracted attention in various fields, especially medicine. In this study, bimetallic CuO/ZnO nanostructures were biosynthesized using plant extracts. The plant-mediated synthesis nanoparticles were characterized by Transmission electron microscopy (TEM), X-ray diffraction analysis (XRD), Field Emission Scanning Electron Microscopy (FESEM) and Energy-Dispersive Spectroscopy (EDAX). The cytotoxicity of plant-mediated synthesis bimetallic nanoparticles and the synergistic effects of these nanoparticles in combination with the anticancer drug doxorubicin on MCF-7 cancer cells were evaluated by MTT assay.
引用
收藏
页码:441 / 447
页数:7
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