Cytotoxicity evaluation of environmentally friendly synthesis Copper/Zinc bimetallic nanoparticles on MCF-7 cancer cells

被引：36

作者：

Zadeh, Firoozeh Abolhasani ^{[1
]}

Bokov, Dmitry Olegovich ^{[2
,3
]}

Salahdin, Omar Dheyauldeen ^{[4
]}

Abdelbasset, Walid Kamal ^{[5
,6
]}

Jawad, Mohammed Abed ^{[7
]}

Kadhim, Mustafa M. ^{[8
,9
,10
]}

Qasim, Maytham T. ^{[11
]}

Kzar, Hamzah H. ^{[12
]}

Al-Gazally, Moaed E. ^{[13
]}

Mustafa, Yasser Fakri ^{[14
]}

Khatami, M. ^{[15
]}

机构：

[1] Kerman Univ Med Sci, Fac Med, Dept Surg, Kerman, Iran

[2] Sechenov First Moscow State Med Univ, Inst Pharm, 8 Trubetskaya St,Bldg 2, Moscow 119991, Russia

[3] Fed Res Ctr Nutr Biotechnol & Food Safety, Lab Food Chem, 2-14 Ustyinsky Pr, Moscow 109240, Russia

[4] Dept Al Maarif Univ Coll, Med Lab Tech, Anbar Ramadi, Iraq

[5] Prince Sattam Bin Abdulaziz Univ, Coll Appl Med Sci, Dept Hlth & Rehabil Sci, Al Kharj, Saudi Arabia

[6] Cairo Univ, Kasr Al Aini Hosp, Dept Phys Therapy, Giza, Egypt

[7] Al Nisour Univ Coll, Baghdad, Iraq

[8] Kut Univ Coll, Dept Dent, Kut 52001, Wasit, Iraq

[9] Islamic Univ, Coll Tech Engn, Najaf, Iraq

[10] Osol Aldeen Univ Coll, Dept Pharm, Baghdad, Iraq

[11] Al Ayen Univ, Coll Hlth & Med Technol, Dept Anesthesia, Thi Qar, Iraq

[12] Al Qasim Green Univ, Coll Vet Med, Dept Chem, Al Qasim, Iraq

[13] Univ Al Ameed, Coll Med, Karbala, Iraq

[14] Univ Mosul, Coll Pharm, Dept Pharmaceut Chem, Mosul 41001, Iraq

[15] Environm Res Ctr, Dept Environm Kerman, Kerman, Iran

来源：

RENDICONTI LINCEI-SCIENZE FISICHE E NATURALI | 2022年 / 33卷 / 02期

关键词：

Cytotoxicity; Environmentally friendly; Copper; Zinc bimetallic nanoparticle; MCF-7 cancer cells; MTT assay; GREEN SYNTHESIS; ZIRCONIA CERAMICS; CHIP THICKNESS; LUBRICATION; HEALTH; AG;

D O I：

10.1007/s12210-022-01064-x

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Bimetallic nanoparticles offer unique chemical, physical and optical properties that are not available for monometallic nanoparticles. Bimetallic nanoparticles play a major role in various therapeutic, industrial and energy fields. Recently, nanoparticles of Copper/Zinc bimetallic nanoparticles have attracted attention in various fields, especially medicine. In this study, bimetallic CuO/ZnO nanostructures were biosynthesized using plant extracts. The plant-mediated synthesis nanoparticles were characterized by Transmission electron microscopy (TEM), X-ray diffraction analysis (XRD), Field Emission Scanning Electron Microscopy (FESEM) and Energy-Dispersive Spectroscopy (EDAX). The cytotoxicity of plant-mediated synthesis bimetallic nanoparticles and the synergistic effects of these nanoparticles in combination with the anticancer drug doxorubicin on MCF-7 cancer cells were evaluated by MTT assay.

引用

页码：441 / 447

页数：7

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