Can the Irradiated Brain Be Salvaged by Oligodendrocyte Precursor Transplantation?

被引:6
|
作者
Harrisingh, Marie C. [1 ]
Ffrench-Constant, Charles [1 ]
机构
[1] Univ Edinburgh, MRC Ctr Regenerat Med, Edinburgh EH16 4UU, Midlothian, Scotland
关键词
PROGENITOR CELLS; CNS;
D O I
10.1016/j.stem.2015.01.010
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Radiotherapy is a mainstay of brain cancer treatment, but it causes significant complications. In this issue of Cell Stem Cell, Piao et al. (2015) derive oligodendrocyte precursors from human embryonic stem cells and show that engrafted cells replenish depleted precursor numbers, generate new myelin, and reverse behavioral defects in irradiated rats.
引用
收藏
页码:113 / 114
页数:2
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