Personalized medicine for individuals with Down syndrome

被引：4
|
作者：
McCabe, Linda L. [1 ,2 ,3 ]
McCabe, Edward R. B. [1 ,3 ]
机构：
[1] Univ Colorado, Sch Med, Linda Crnic Inst Syndrome, Aurora, CO 80045 USA
[2] Univ Colorado, Sch Med, Ctr Bioeth & Humanities, Aurora, CO 80045 USA
[3] Univ Colorado, Sch Med, Dept Pediat, Aurora, CO 80045 USA
来源：
MOLECULAR GENETICS AND METABOLISM | 2011年 / 104卷 / 1-2期
关键词：
Down syndrome; Personalized medicine; SIMPLE MENDELIAN DISORDERS; DOCK8;
D O I：
10.1016/j.ymgme.2011.07.008
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
As the cost of whole genome analysis decreases, we have the opportunity to explore the interactions of various gene changes in an individual that lead to their particular phenotype. This will provide the ability to move from the epidemiologic study of groups, in which, the individuals are treated collectively and homogenously, to personalized medicine, and a model in which the individual is recognized and treated as a distinct entity. We will be applying personalized medicine to individuals with Down syndrome in order to understand and develop biomarkers for increased risk of co-morbidities. Personalized medicine will change the "culture of intractability" of Down syndrome. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码：7 / 9
页数：3
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