Clonal Hematopoiesis: A New Layer in the Liquid Biopsy Story in Lung Cancer

被引：39

作者：

Bauml, Joshua ^{[1
]}

Levy, Benjamin ^{[2
]}

机构：

[1] Univ Penn, Abrahamson Canc Ctr, Philadelphia, PA 19104 USA

[2] Sibley Mem Hosp, Johns Hopkins Sidney Kimmel Canc Ctr, Washington, DC USA

来源：

CLINICAL CANCER RESEARCH | 2018年 / 24卷 / 18期

关键词：

OF-AMERICAN-PATHOLOGISTS;

D O I：

10.1158/1078-0432.CCR-18-0969

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cell-free DNA (cfDNA) is a unique biospecimen that contains multiple sources of DNA, including tumor, germline, fetal, and others. Clonal hematopoiesis, a process that leads to expansion of mutations in peripheral blood cells, is an additional source of DNA that adds a layer of complexity when interpreting results. Clin Cancer Res; 24(18); 4352-4. (C) 2018 AACR.

引用

页码：4352 / 4354

页数：3

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