New fACEs to the renin-angiotensin system

被引：52

作者：

Fleming, I ^{[1
]}

Kohlstedt, K ^{[1
]}

Busse, R ^{[1
]}

机构：

[1] Univ Frankfurt, Inst Kardiovaskulare Physiol, Vasc Signaling Grp, D-6000 Frankfurt, Germany

来源：

PHYSIOLOGY | 2005年 / 20卷

关键词：

D O I：

10.1152/physiol.00003.2005

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Inhibition of the angiotensin-converting enzyme (ACE) protects against the progression of several cardiovascular diseases. Recent evidence suggests that some of the beneficial effects of ACE inhibitors can be attributed to the activation of a distinct ACE signaling cascade rather than to the changes in angiotensin II and bradykinin levels. Moreover, at least one other ACE homolog (ACE2) plays a significant role in the regulation of heart and kidney function.

引用

页码：91 / 95

页数：5

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