AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3

被引：305
|
作者：
Wunderlich, M. [1 ]
Chou, F-S [1 ]
Link, K. A. [1 ]
Mizukawa, B. [2 ]
Perry, R. L. [3 ]
Carroll, M. [4 ]
Mulloy, J. C. [1 ]
机构：
[1] Cincinnati Childrens Hosp, Med Ctr, Div Expt Hematol & Canc Biol, Cincinnati, OH USA
[2] Cincinnati Childrens Hosp, Med Ctr, Div Hematol & Oncol, Cincinnati, OH USA
[3] Childrens Hosp Philadelphia, Div Oncol, Philadelphia, PA 19104 USA
[4] Univ Penn, Div Hematol & Oncol, Philadelphia, PA 19104 USA
来源：
LEUKEMIA | 2010年 / 24卷 / 10期
关键词：
HEMATOPOIETIC STEM-CELLS; ACUTE MYELOID-LEUKEMIA; MODEL; ENGRAFTMENT;
D O I：
10.1038/leu.2010.158
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：1785 / 1788
页数：4
相关论文
共 50 条
  • [41] Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung
    Willinger, Tim
    Rongvaux, Anthony
    Takizawa, Hitoshi
    Yancopoulos, George D.
    Valenzuela, David M.
    Murphy, Andrew J.
    Auerbach, Wojtek
    Eynon, Elizabeth E.
    Stevens, Sean
    Manz, Markus G.
    Flavell, Richard A.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (06) : 2390 - 2395
  • [42] NOD/SCID mice engineered to produce human IL-3, GM-CSF and steel factor show enhanced human granulopoiesis and decreased erythropoiesis, mobilization of human clonogenic progenitors and decreased maintenance of more primitive human cells
    Nicolini, F
    Cashman, J
    Humphries, K
    Michallet, M
    Eaves, C
    EXPERIMENTAL HEMATOLOGY, 2003, 31 (07) : 138 - 138
  • [43] Expansion of bcr/abl negative progenitor cells in LTBMC by MIP-1alpha, SCF, IL-3, IL-6 and GM-CSF
    Keil, F
    Louda, N
    Chen, X
    Petzer, A
    Prinz, E
    Kalhs, P
    Worel, N
    Lechner, K
    Greinix, HT
    BONE MARROW TRANSPLANTATION, 2001, 27 : S144 - S144
  • [44] HUMAN IL-5 BUT NOT IL-3 AND GM-CSF PROMOTES THE SURVIVAL OF GUINEA-PIG PERITONEAL EOSINOPHILS INVITRO
    WEBBER, SE
    DEBRITO, FB
    MCCARTHY, C
    WOOD, LM
    AMERICAN REVIEW OF RESPIRATORY DISEASE, 1993, 147 (04): : A821 - A821
  • [45] STIMULATION OF CLONAL GROWTH OF HUMAN COLORECTAL TUMOR-CELLS BY IL-3 AND GM-CSF - MODULATION OF 5-FU CYTOTOXICITY BY GM-CSF
    BERDEL, WE
    DANHAUSERRIEDL, S
    STEINHAUSER, G
    RASTETTER, J
    ONKOLOGIE, 1990, 13 (06): : 437 - 443
  • [46] Do IL-3/GM-CSF effect on the myofibroblastic differentiation of human adipose derived stromal cells?
    Lee, Jae-Sun
    Tae, Son-Seung
    Kim, Deok-Yeol
    Han, Seung-Kyu
    Kim, Woo-Kyung
    Dhong, Eun-Sang
    EXPERIMENTAL CELL RESEARCH, 2017, 355 (02) : 67 - 82
  • [47] The IL-3, IL-5, and GM-CSF common receptor beta chain mediates oncogenic activity of FLT3-ITD-positive AML
    Charlet, Anne
    Kappenstein, Max
    Keye, Philip
    Klasener, Kathrin
    Endres, Cornelia
    Poggio, Teresa
    Gorantla, Sivahari P.
    Kreutmair, Stefanie
    Sanger, Jana
    Illert, Anna L.
    Miething, Cornelius
    Reth, Michael
    Duyster, Justus
    Rummelt, Christoph
    von Bubnoff, Nikolas
    LEUKEMIA, 2022, 36 (03) : 701 - 711
  • [48] Naive human mast cells (MC) transcribe IL-3, IL-5 and GM-CSF mRNA and secrete IL-5 and GM-CSF protein following Fc epsilon RI ligation.
    Bressler, RB
    Lesko, J
    Jones, M
    Wasserman, M
    Dickason, RR
    Cook, S
    Huston, MM
    Huston, DP
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1996, 97 (01) : 331 - 331
  • [49] The IL-3, IL-5, and GM-CSF common receptor beta chain mediates oncogenic activity of FLT3-ITD-positive AML
    Anne Charlet
    Max Kappenstein
    Philip Keye
    Kathrin Kläsener
    Cornelia Endres
    Teresa Poggio
    Sivahari P. Gorantla
    Stefanie Kreutmair
    Jana Sänger
    Anna L. Illert
    Cornelius Miething
    Michael Reth
    Justus Duyster
    Christoph Rummelt
    Nikolas von Bubnoff
    Leukemia, 2022, 36 : 701 - 711
  • [50] Myeloproliferative disorder and leukaemia in mice induced by different classes of constitutive mutants of the human IL-3/IL-5/GM-CSF receptor common β subunit
    Matthew P McCormack
    Thomas J Gonda
    Oncogene, 1999, 18 : 7190 - 7199
12345