Biocatalysis in polymer-supported synthesis: Enzyme-labile linker groups

被引：0
|
作者：
Reents, R
Jeyaraj, DA
Waldmann, H
机构：
[1] Max Planck Inst Mol Physiol, Abt Chem Biol, D-44227 Dortmund, Germany
[2] Univ Dortmund, Fachbereich 3, D-44221 Dortmund, Germany
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2001年 / 343卷 / 6-7期
关键词：
cleavage reactions; combinatorial chemistry; enzyme catalysis; linker groups;
D O I：
10.1002/1615-4169(200108)343:6/7<501::AID-ADSC501>3.3.CO;2-4
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The development or new and broadly applicable linker groups which are stable under a variety of reaction conditions and allow release of the desired products from polymeric supports under very mild conditions is of great interest for organic synthesis and combinatorial chemistry. In this review we summarize the results of the research activities directed towards the introduction of enzyme-labile linkers which yield a variety of different target molecules through enzymatic cleavage from different polymeric supports.
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页码：501 / 513
页数：13
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