Solid phase synthesis of β-lactams via the Staudinger reaction

被引：21
|
作者：
Singh, R [1 ]
Nuss, JM [1 ]
机构：
[1] Chiron Corp, Emeryville, CA 94608 USA
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 07期
关键词：
D O I：
10.1016/S0040-4039(98)02672-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of cis-azetidinones on solid support via the Staudinger reaction is described. The final products are obtained in high purity with no purification required. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：1249 / 1252
页数：4
相关论文
共 50 条
  • [41] Synthesis of β-lactams from a N-rhenaimine:: Effect of the transition metal on the energetic profile of the Staudinger reaction
    Hevia, E
    Pérez, J
    Riera, V
    Miguel, D
    Campomanes, P
    Menéndez, MI
    Sordo, TL
    García-Granda, S
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (13) : 3706 - 3707
  • [42] Modulating steric effects in diastereoselective Staudinger reaction: Synthesis of optically pure cis-beta-lactams
    Jayaraman, M
    Srirajan, V
    Deshmukh, ARAS
    Bhawal, BM
    TETRAHEDRON, 1996, 52 (10) : 3741 - 3756
  • [43] Synthesis of cis bis-β-lactams via Staudinger cycloaddition reaction using C2-symmetric 1,2-diamines
    Shaikh, AL
    Puranik, VG
    Deshmukh, ARAS
    TETRAHEDRON, 2005, 61 (09) : 2441 - 2451
  • [44] Diastereoselective synthesis of highly constrained spiro-β-lactams by the staudinger reaction using an unsymmetrical bicyclic ketene
    Trabocchi, Andrea
    Lalli, Claudia
    Guarna, Francesco
    Guarna, Antonio
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2007, 2007 (27) : 4594 - 4599
  • [45] Solid-phase synthesis of β-lactams via the ester enolate-imine condensation route
    Schunk, S
    Enders, D
    ORGANIC LETTERS, 2000, 2 (07) : 907 - 910
  • [46] Switch Peptide via Staudinger Reaction
    Nepomniaschiy, Natalia
    Grimminger, Valerie
    Cohen, Aviv
    DiGiovanni, Saviana
    Lashuel, Hilal A.
    Brik, Ashraf
    ORGANIC LETTERS, 2008, 10 (22) : 5243 - 5246
  • [47] Diastereoselective Synthesis of γ-Lactams and δ-Lactams via a Conjugate Addition-Initiated Tandem Reaction
    Gan, Miaomiao
    Jiang, Lan
    Li, Zhengning
    SYNLETT, 2019, 30 (12) : 1447 - 1451
  • [48] SOLUTION AND SOLID-PHASE SYNTHESIS OF POLYCYCLIC LACTAMS VIA 1,3 DIPOLAR CYCLOADDITIONS
    MARX, MA
    LOUER, CT
    BARTLETT, PA
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1995, 209 : 332 - ORGN
  • [49] Solid-phase synthesis of β-lactams via the ester enolate-imine condensation route.
    Enders, D
    Schunk, S
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 221 : U110 - U110
  • [50] Solid phase synthesis of oxazolidinones via a novel cyclisation/cleavage reaction
    Buchstaller, HP
    TETRAHEDRON, 1998, 54 (14) : 3465 - 3470
12345