Solid phase synthesis of β-lactams via the Staudinger reaction

被引:21
|
作者
Singh, R [1 ]
Nuss, JM [1 ]
机构
[1] Chiron Corp, Emeryville, CA 94608 USA
关键词
D O I
10.1016/S0040-4039(98)02672-0
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of cis-azetidinones on solid support via the Staudinger reaction is described. The final products are obtained in high purity with no purification required. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1249 / 1252
页数:4
相关论文
共 50 条
  • [11] Asymmetric synthesis of β-lactams by Staudinger ketene-imine cycloaddition reaction
    Palomo, C
    Aizpurua, JM
    Ganboa, I
    Oiarbide, M
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 1999, 1999 (12) : 3223 - 3235
  • [12] Stereospecific Synthesis of -Lactams from Heterocyclic Imines Using the Staudinger Reaction
    Stalling, T.
    Johannes, K.
    Polina, S.
    Martens, J.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2013, 50 (03) : 654 - 659
  • [13] ASYMMETRIC-SYNTHESIS OF BETA-LACTAMS AND N-BENZOYL-3-PHENYLISOSERINES VIA THE STAUDINGER REACTION
    GEORG, GI
    MASHAVA, PM
    AKGUN, E
    MILSTEAD, MW
    TETRAHEDRON LETTERS, 1991, 32 (27) : 3151 - 3154
  • [14] Asymmetric synthesis of 3-amino-β-lactams via staudinger ketene-imine cycloaddition reaction: (Review)
    Palomo C.
    Aizpurua J.M.
    Chemistry of Heterocyclic Compounds, 1998, 34 (11) : 1222 - 1236
  • [15] Carbocation catalyzed carboxylic acid activation in Staudinger reaction for stereoselective synthesis of β-lactams
    Rai, Ankita
    Singh, Puneet K.
    Shukla, Prashant
    Rai, Vijai K.
    TETRAHEDRON LETTERS, 2016, 57 (46) : 5084 - 5088
  • [16] Solid-phase synthesis of β-lactams via the Miller hydroxamate approach
    Meloni, MM
    Taddei, M
    ORGANIC LETTERS, 2001, 3 (03) : 337 - 340
  • [17] Synthesis of structurally diverse 2-azetidinones via staudinger reaction on a solid support
    Department of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran
    不详
    Bull. Chem. Soc. Jpn., 3 (320-327):
  • [18] Synthesis of Structurally Diverse 2-Azetidinones via Staudinger Reaction on a Solid Support
    Jarrahpour, Aliasghar
    Fadavi, Abdolhamid
    Zarei, Maaroof
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 2011, 84 (03) : 320 - 327
  • [19] Expedited access to β-lactams via a telescoped three-component Staudinger reaction in flow
    Minuto, Federica
    Basso, Andrea
    Baumann, Marcus
    JOURNAL OF FLOW CHEMISTRY, 2024, 14 (04) : 615 - 621
  • [20] Synthesis of New Polyfluoro Oligonucleotides via Staudinger Reaction
    Klabenkova, Kristina
    Zakhryamina, Alyona
    Burakova, Ekaterina
    Bizyaev, Sergei
    Fokina, Alesya
    Stetsenko, Dmitry
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2025, 26 (01)