Stereoselective synthesis of microcarpalide

被引:23
|
作者
Ishigami, K [1 ]
Watanabe, H [1 ]
Kitahara, T [1 ]
机构
[1] Univ Tokyo, Grad Sch Agr & Life Sci, Dept Appl Biol Chem, Bunkyo Ku, Tokyo 1138657, Japan
关键词
microcarpalide; microfilament disrupting agent; macrolactonization; Julia olefination; sharpless asymmetric dihydroxylation;
D O I
10.1016/j.tet.2005.05.057
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Microcarpalide is a strong microfilament disrupting agent. The convergent and stereoselective synthesis of microcarpalide was succeeded via Julia olefination and macrolactonization. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:7546 / 7553
页数:8
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