Stereoselective synthesis of microcarpalide

被引:23
|
作者
Ishigami, K [1 ]
Watanabe, H [1 ]
Kitahara, T [1 ]
机构
[1] Univ Tokyo, Grad Sch Agr & Life Sci, Dept Appl Biol Chem, Bunkyo Ku, Tokyo 1138657, Japan
关键词
microcarpalide; microfilament disrupting agent; macrolactonization; Julia olefination; sharpless asymmetric dihydroxylation;
D O I
10.1016/j.tet.2005.05.057
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Microcarpalide is a strong microfilament disrupting agent. The convergent and stereoselective synthesis of microcarpalide was succeeded via Julia olefination and macrolactonization. (c) 2005 Elsevier Ltd. All rights reserved.
引用
收藏
页码:7546 / 7553
页数:8
相关论文
共 50 条
  • [41] Stereoselective synthesis of tilivalline
    Nagasaka, T
    Koseki, Y
    JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (20): : 6797 - 6801
  • [42] Stereoselective synthesis of selenosteroids
    Rodrigues, Oscar E. D.
    de Souza, Diego
    Soares, Letiere C.
    Dornelles, Luciano
    Burrow, Robert A.
    Appelt, Helmoz R.
    Alves, Camila F.
    Alves, Diego
    Braga, Antonio L.
    TETRAHEDRON LETTERS, 2010, 51 (17) : 2237 - 2240
  • [43] A stereoselective synthesis of dihydrosphingosine
    Fernandes, RA
    Kumar, P
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2000, 2000 (20) : 3447 - 3449
  • [44] Stereoselective synthesis of (±)-tacamonine
    Ho, Tse-Lok
    Lin, Qi-xian
    TETRAHEDRON, 2008, 64 (45) : 10401 - 10405
  • [45] Stereoselective synthesis of (-)-cytoxazone
    Carda, M
    González, F
    Sánchez, R
    Marco, JA
    TETRAHEDRON-ASYMMETRY, 2002, 13 (09) : 1005 - 1010
  • [46] STEREOSELECTIVE SYNTHESIS OF (+/-)-TRICHODIENE
    HARDING, KE
    CLEMENT, KS
    TSENG, CY
    JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (14): : 4403 - 4410
  • [47] A stereoselective synthesis of (-)-tetrahydrolipstatin
    Ghosh, AK
    Liu, CF
    CHEMICAL COMMUNICATIONS, 1999, (17) : 1743 - 1744
  • [48] The stereoselective synthesis of neolignans
    Sefkow, M
    SYNTHESIS-STUTTGART, 2003, (17): : 2595 - 2625
  • [49] A STEREOSELECTIVE SYNTHESIS OF SQUALENE
    CORNFORTH, JW
    CORNFORTH, RH
    MATHEW, KK
    JOURNAL OF THE CHEMICAL SOCIETY, 1959, (JUL-A): : 2539 - 2547
  • [50] Stereoselective synthesis of α,α′-biprofines
    Vartak, AP
    Young, VG
    Johnson, RL
    ORGANIC LETTERS, 2005, 7 (01) : 35 - 38