Combinatorial Synthesis of 3,5-Dimethylene Substituted 1,2,4-Triazoles

被引：0

作者：

Woodard, Scott S. ^{[1
]}

Jerome, Kevin D. ^{[1
]}

机构：

[1] Pfizer Inc, Global Res & Dev, Med & Parallel Chem, Chesterfield, MO 63017 USA

来源：

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING | 2011年 / 14卷 / 02期

关键词：

Cyclizations; combinatorial chemistry; 1,2,4-triazoles; Pinner reaction; hydrazides; imidates; 3,5-DISUBSTITUTED 1,2,4-TRIAZOLES; MIT IMIDSAUREESTERN; ANTIBACTERIAL; CYCLIZATION; ANTAGONISTS; AGENTS; ROUTE;

D O I：

暂无

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Combinatorial cyclizations of imidates and hydrazides with methylene linked R groups, generated from the corresponding nitriles and carboxylic acids, respectively, provided a large library of 3,5-dimethylene substituted 1,2,4-trizoles. [GRAPHICS] .

引用

页码：132 / 137

页数：6

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