Translating stem cell research to the clinic: A constant crosstalk between basic and applied research

被引：0

作者：

Raineteau, Olivier ^{[1
]}

机构：

[1] Univ Zurich, ETHZ, Brain Res Inst, CH-8057 Zurich, Switzerland

来源：

TRANSLATIONAL NEUROSCIENCE | 2012年 / 3卷 / 02期

关键词：

Cell replacement therapy; Disease modeling; Induced-pluripotent stem cells; Neuronal subtypes; Neuronal specification; Translational research; MIDBRAIN DOPAMINE NEURONS; GROWTH-FACTOR-ALPHA; HUMAN ES; HUMAN FIBROBLASTS; CEREBRAL-CORTEX; DIFFERENTIATION; BRAIN; TRANSPLANTATION; MOUSE; INHIBITION;

D O I：

10.2478/s13380-012-0016-y

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Pluripotent stem cells hold great promise for the generation of patient-specific cells for disease modeling and regenerative medicine. Focusing on a recent study reporting the successful generation of midbrain dopaminergic neurons and their efficient grafting in animal models of Parkinson's disease, I discuss how crosstalk between basic and applied stem cell research more generally paves the road toward clinical translation.

引用

页码：217 / 221

页数：5

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