Translating stem cell research to the clinic: A constant crosstalk between basic and applied research

被引：0
|
作者：
Raineteau, Olivier [1 ]
机构：
[1] Univ Zurich, ETHZ, Brain Res Inst, CH-8057 Zurich, Switzerland
来源：
TRANSLATIONAL NEUROSCIENCE | 2012年 / 3卷 / 02期
关键词：
Cell replacement therapy; Disease modeling; Induced-pluripotent stem cells; Neuronal subtypes; Neuronal specification; Translational research; MIDBRAIN DOPAMINE NEURONS; GROWTH-FACTOR-ALPHA; HUMAN ES; HUMAN FIBROBLASTS; CEREBRAL-CORTEX; DIFFERENTIATION; BRAIN; TRANSPLANTATION; MOUSE; INHIBITION;
D O I：
10.2478/s13380-012-0016-y
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Pluripotent stem cells hold great promise for the generation of patient-specific cells for disease modeling and regenerative medicine. Focusing on a recent study reporting the successful generation of midbrain dopaminergic neurons and their efficient grafting in animal models of Parkinson's disease, I discuss how crosstalk between basic and applied stem cell research more generally paves the road toward clinical translation.
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页码：217 / 221
页数：5
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