Synthetic approaches to the 2006 new drugs

被引：17
|
作者：
Liu, Kevin K. -C. [2 ]
Sakya, Subas A.
Li, Jin
机构：
[1] Pfizer Inc, La Jolla, CA 92037 USA
[2] Pfizer Inc, Groton, CT 06340 USA
[3] Shenogen Pharm Grp, Beijing, Peoples R China
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2007年 / 7卷 / 12期
关键词：
synthesis; new drug; new chemical entities; medicine; therapeutic agents;
D O I：
10.2174/138955707782795629
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as drug-like leads for designing future new drugs. To these ends, this review covers the syntheses of 16 NCEs marketed in 2006.
引用
收藏
页码：1255 / 1269
页数：15
相关论文
共 50 条
  • [31] NEW APPROACHES TO ANTIPARASITIC DRUGS
    CERAMI, A
    FASEB JOURNAL, 1993, 7 (07): : A1052 - A1052
  • [32] Synthetic Approaches to Contemporary Drugs that Contain the Cyclopropyl Moiety
    Casar, Zdenko
    SYNTHESIS-STUTTGART, 2020, 52 (09): : 1315 - 1345
  • [33] Synthetic Approaches to the New Drugs Approved During 2015 (vol 60, pg 6480, 2017)
    Flick, Andrew C.
    Ding, Hong X.
    Leverett, Carolyn A.
    Kyne, Robert E., Jr.
    Liu, Kevin K-C.
    Fink, Sarah J.
    O'Donnell, Christopher J.
    JOURNAL OF MEDICINAL CHEMISTRY, 2017, 60 (20) : 8680 - 8680
  • [34] New synthetic drugs require new policies
    Pardo, Bryce
    Taylor, Jirka
    Caulkins, Jon
    Reuter, Peter
    Kilmer, Beau
    ADDICTION, 2021, 116 (06) : 1317 - 1318
  • [35] DESIGNER DRUGS - THE CHALLENGE OF THE NEW SYNTHETIC DRUGS OF ABUSE
    HENDERSON, GL
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1986, 192 : 12 - CHAL
  • [36] NEW ANTIHYPERTENSIVE DRUGS AND NEW APPROACHES TO HYPERTENSION
    JAMIESON, A
    REID, JL
    CURRENT OPINION IN CARDIOLOGY, 1992, 7 (05) : 789 - 795
  • [37] New synthetic drugs in the European Union
    King, LA
    Van-der Meer, AJP
    SCIENCE & JUSTICE, 2001, 41 (03) : 200 - 202
  • [38] Boranophosphate oligonucleotides: New synthetic approaches
    Sergueev, D
    Hasan, A
    Ramaswamy, M
    Shaw, BR
    NUCLEOSIDES & NUCLEOTIDES, 1997, 16 (7-9): : 1533 - 1538
  • [39] SYNTHETIC APPROACHES TO NEW REGIOISOMERS OF AZT
    PURDY, DF
    ZINTEK, LB
    NAIR, V
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1993, 205 : 81 - CARB
  • [40] Synthetic biology approaches to new chemistry
    Chang, Michelle
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
12345