Synthetic approaches to the 2006 new drugs

被引：17
|
作者：
Liu, Kevin K. -C. [2 ]
Sakya, Subas A.
Li, Jin
机构：
[1] Pfizer Inc, La Jolla, CA 92037 USA
[2] Pfizer Inc, Groton, CT 06340 USA
[3] Shenogen Pharm Grp, Beijing, Peoples R China
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2007年 / 7卷 / 12期
关键词：
synthesis; new drug; new chemical entities; medicine; therapeutic agents;
D O I：
10.2174/138955707782795629
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as drug-like leads for designing future new drugs. To these ends, this review covers the syntheses of 16 NCEs marketed in 2006.
引用
收藏
页码：1255 / 1269
页数：15
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