Synthesis of New Diaryl(hetaryl)ethylphosphonic Acids

被引：0
|
作者：
Sadykova, Yu M. [1 ]
Zalaltdinova, A., V [2 ]
Smailov, A. K. [2 ]
Burilov, A. R. [1 ]
Pudovik, M. A. [1 ]
机构：
[1] Russian Acad Sci, Arbuzov Inst Organ & Phys Chem, Fed Res Ctr, Kazan Sci Ctr, Kazan 420088, Russia
[2] Kazan Natl Res Technol Univ, Kazan 420015, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2021年 / 91卷 / 07期
基金：
俄罗斯基础研究基金会;
关键词：
diaryl(hetaryl)ethylphosphonic acids; (2-ethoxyvinyl)phosphonic dichloride; 4-hydroxy-6methyl-2-pyrone; 4-hydroxycoumarin; thymol; carvacrol; MOTIF;
D O I：
10.1134/S1070363221070215
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An original, new method for the synthesis of previously unknown diaryl(hetaryl)ethylphosphonic acids containing pharmacophoric fragments was developed as a result of the acid-catalyzed reaction of (2-ethoxyvinyl)phosphonic dichloride with heterocyclic compounds such as 4-hydroxy-6-methyl-2-pyrone, 4-hydroxycoumarin, and also thymol and carvacrol containing a hydroxyl group. Composition and structure of all diaryl(hetaryl)ethylphosphonic acids were confirmed according to H-1, C-13 and P-31 NMR, IR spectroscopy, mass spectrometry and elemental analysis data.
引用
收藏
页码：1420 / 1423
页数：4
相关论文
共 50 条
  • [1] Synthesis of New Diaryl(hetaryl)ethylphosphonic Acids
    Yu. M. Sadykova
    A. V. Zalaltdinova
    А. K. Smailov
    А. R. Burilov
    М. А. Pudovik
    Russian Journal of General Chemistry, 2021, 91 : 1420 - 1423
  • [2] Facile synthesis of photoactive diaryl(hetaryl) cyclopentenes by ionic hydrogenation
    Lvov, Andrey G.
    Bulich, Ekaterina Yu.
    Metelitsa, Anatoly V.
    Shirinian, Valerii Z.
    RSC ADVANCES, 2016, 6 (64): : 59016 - 59020
  • [3] SYNTHESIS OF 2-(PYRIDYL)ETHYLPHOSPHONIC ACIDS AND ESTERS
    MARUSZEWSKAWIECZORKOWSKA, E
    MICHALSKI, J
    JOURNAL OF ORGANIC CHEMISTRY, 1958, 23 (12): : 1886 - 1889
  • [4] SYNTHESIS AND PROPERTIES OF PYRIMIDINYLALKYLPHOSPHONIC ACIDS .5. SYNTHESIS OF BETA-(OXOPYRIMIDYL-N)-ETHYLPHOSPHONIC ACIDS
    REZNIK, VS
    SHVETSOV, YS
    PASHKURO.NG
    IZVESTIYA AKADEMII NAUK SSSR-SERIYA KHIMICHESKAYA, 1973, (02): : 402 - 406
  • [5] A convenient synthesis of 3,4-diaryl(hetaryl)-substituted maleimides and maleic anhydrides
    Shorunov, S. V.
    Krayushkin, M. M.
    Stoyanovich, F. M.
    Irie, M.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2006, 42 (10) : 1490 - 1497
  • [6] A convenient synthesis of 3,4-diaryl(hetaryl)-substituted maleimides and maleic anhydrides
    S. V. Shorunov
    M. M. Krayushkin
    F. M. Stoyanovich
    M. Irie
    Russian Journal of Organic Chemistry, 2006, 42 : 1490 - 1497
  • [7] FISCHER CYCLIZATION OF N,N-DIARYL-HETARYL (AND N-ARYL-HETARYL)HYDRAZINES
    SHARKOVA, NM
    KUCHEROV.NF
    ZAGOREVS.VA
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1974, (11): : 1580 - 1581
  • [8] Synthesis and bioactivity of several new hetaryl sulfonamides
    Taslimi, Parham
    Sujayev, Afsun
    Mamedova, Sevgi
    Kalin, Pinar
    Gulcin, Ilhami
    Sadeghian, Nastaran
    Beydemir, Sukru
    Kufrevioglu, O. Irfan
    Alwasel, Saleh H.
    Farzaliyev, Vagif
    Mamedov, Sabir
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2017, 32 (01) : 137 - 145
  • [9] Synthesis of Diaryl Hydroxyl Dicarboxylic Acids from Amino Acids
    Eronen, Aleksi E. K.
    Mannisto, Jere K.
    Moslova, Karina
    Nieger, Martin
    Heliovaara, Eeva
    Repo, Timo
    JOURNAL OF ORGANIC CHEMISTRY, 2020, 85 (09): : 5799 - 5806
  • [10] NEW SYNTHESIS OF DIARYL CARBODIIMIDES
    KATRITZKY, AR
    NIE, PL
    DONDONI, A
    TASSI, D
    SYNTHETIC COMMUNICATIONS, 1977, 7 (06) : 387 - 392
12345