Eco-friendly synthesis of diverse and valuable 2-pyridones by catalyst- and solvent-free thermal multicomponent domino reaction

被引：42

作者：

Poudel, Tej Narayan ^{[1
]}

Lee, Yong Rok ^{[1
]}

Kim, Sung Hong ^{[2
]}

机构：

[1] Yeungnam Univ, Sch Chem Engn, Kyongsan 712749, South Korea

[2] Korea Basic Sci Inst, Anal Res Div, Daegu Ctr, Taegu 702701, South Korea

来源：

GREEN CHEMISTRY | 2015年 / 17卷 / 09期

基金：

新加坡国家研究基金会;

关键词：

BIOLOGICAL EVALUATION; INHIBITORS; DESIGN; CYCLOADDITION; PYRIDONES; DERIVATIVES; CYCLIZATION; ALKYNES; IDENTIFICATION; CONSTRUCTION;

D O I：

10.1039/c5gc01526j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient and highly eco-friendly synthesis of diverse and functionalized 2-pyridone derivatives in good yield via the thermal multicomponent reaction of 4-oxo-4H-chromene-3-carbaldehydes with 1,3-diketoesters and anilines or primary aliphatic amines under catalyst-and solvent-free conditions is described. This reaction proceeds via domino Knoevenagel condensation/Michael addition/ring opening/ring closure reactions.

引用

页码：4579 / 4586

页数：8

共 50 条

[41] An isocyanide based multi-component reaction under catalyst- and solvent-free conditions for the synthesis of unsymmetrical thioureas
Singh, Karandeep
Sharma, Siddharth
TETRAHEDRON LETTERS, 2017, 58 (03) : 197 - 201
[42] A microwave-mediated catalyst- and solvent-free regioselective Biginelli reaction in the synthesis of highly functionalized novel tetrahydropyrimidines
Harikrishnan, Palani Sokkan
Rajesh, Stephen Michael
Perumal, Subbu
Almansour, Abdulrahman I.
TETRAHEDRON LETTERS, 2013, 54 (09) : 1076 - 1079
[43] Onion (Allium cepa L.) Extract: A Green and Eco-friendly Catalyst for MW-Assisted Solvent-Free Synthesis of Pyrroles via Paal-Knorr Reaction
Marvi, O.
Arshadi, S.
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 60 (03) : 472 - 479
[44] A new synthetic approach to polysubstituted-2-pyridones from enamino esters and diethyl ethoxymethylenemalonate under catalyst- and solvent-free conditions
Zhao, Xian-Liang
Yang, Ke-fang
Zhang, Yan-Ping
Fu, Xiao-Hang
Xu, Li-Wen
TETRAHEDRON LETTERS, 2016, 57 (03) : 321 - 324
[45] Tungstophosphoric acid supported on titania as an eco-friendly, green and reusable catalyst for the solvent-free Hantzsch multi-component condensation
Rafiee, Ezzat
Eavani, Sara
Rashidzadeh, Solmaz
Joshaghani, Mohammad
HETEROCYCLES, 2008, 75 (09) : 2225 - 2233
[46] Efficient acylation and sulfation of carbohydrates using sulfamic acid, a mild, eco-friendly catalyst under organic solvent-free conditions
Santra, Abhishek
Guchhait, Goutam
Misra, Anup Kumar
GREEN CHEMISTRY, 2011, 13 (05) : 1345 - 1351
[47] Blue LED induced solvent-free multicomponent reactions among aryl diazoacetates, pyridine derivatives and maleimides: direct eco-friendly synthesis of densely functionalized itaconimides
Maiti, Debajit
Das, Ranajit
Prabakar, Tejas
Sen, Subhabrata
GREEN CHEMISTRY, 2022, 24 (07) : 3001 - 3008
[48] An Eco-friendly Three Component Manifold for the Synthesis of α-Aminophosphonates under Catalyst and Solvent-free Conditions, X-ray Characterization and Their Evaluation as Anticancer Agents
Mirzaei, Mahdi
Eshghi, Hossein
Rahimizadeh, Mohammad
Bakavoli, Mehdi
Matin, Maryam M.
Hosseinymehr, Minoo
Rudbari, Hadi Amiri
Bruno, Giuseppe
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2015, 62 (12) : 1087 - 1096
[49] Eco-friendly catalyst design: Transforming volcanic lava ashes into sustainable synthesis of glycerol carbonate from glycerol in one pot solvent-free route
Kandola, Isack
Kivevele, Thomas
Hilonga, Askwar
Kichonge, Baraka
Maina, Paulo
Ramkat, Rose C.
Castro-Ocampo, Orlando
Delesma, Cornelio
Muniz, Jesus
Okoye, Patrick U.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING, 2025, 13 (02):
[50] A caffeine-based ionic liquid as a novel and eco-friendly catalyst for the synthesis of 1,8-dioxo-octahydroxanthenes under solvent-free conditions
Masoumeh Salami
Ali Ezabadi
Research on Chemical Intermediates, 2019, 45 : 3673 - 3686

← 1 2 3 4 5 →