Eco-friendly synthesis of diverse and valuable 2-pyridones by catalyst- and solvent-free thermal multicomponent domino reaction

被引：42
|
作者：
Poudel, Tej Narayan [1 ]
Lee, Yong Rok [1 ]
Kim, Sung Hong [2 ]
机构：
[1] Yeungnam Univ, Sch Chem Engn, Kyongsan 712749, South Korea
[2] Korea Basic Sci Inst, Anal Res Div, Daegu Ctr, Taegu 702701, South Korea
来源：
GREEN CHEMISTRY | 2015年 / 17卷 / 09期
基金：
新加坡国家研究基金会;
关键词：
BIOLOGICAL EVALUATION; INHIBITORS; DESIGN; CYCLOADDITION; PYRIDONES; DERIVATIVES; CYCLIZATION; ALKYNES; IDENTIFICATION; CONSTRUCTION;
D O I：
10.1039/c5gc01526j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient and highly eco-friendly synthesis of diverse and functionalized 2-pyridone derivatives in good yield via the thermal multicomponent reaction of 4-oxo-4H-chromene-3-carbaldehydes with 1,3-diketoesters and anilines or primary aliphatic amines under catalyst-and solvent-free conditions is described. This reaction proceeds via domino Knoevenagel condensation/Michael addition/ring opening/ring closure reactions.
引用
收藏
页码：4579 / 4586
页数：8
相关论文
共 50 条
  • [31] Catalyst- and Solvent-Free Room Temperature Synthesis of α-Aminophosphonates: Green Accomplishment of the Kabachnik-Fields Reaction
    Gabor, Dora
    Pollak, Patrik
    Volk, Balazs
    Dancso, Andras
    Simig, Gyula
    Milen, Matyas
    CHEMISTRYSELECT, 2023, 8 (26):
  • [32] An Eco-friendly Solvent-free Synthesis of Trisubstituted Methane Derivatives Catalyzed by Magnetic Iron Oxide Nanoparticles as a Highly Efficient and Recyclable Catalyst
    Eskandari, Khalil
    Khodabakhshi, Saeed
    LETTERS IN ORGANIC CHEMISTRY, 2018, 15 (06) : 463 - 471
  • [33] Catalyst- and Solvent-Free Synthesis of N-Acylhydrazones via Solid-State Melt Reaction
    Mayurachayakul, Pipattra
    Niamnont, Nakorn
    Chaiseeda, Kittichai
    Chantarasriwong, Oraphin
    ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2022, 11 (05)
  • [34] Eco-Friendly and Facile Synthesis of Diverse Heterocycles Via Zirconia Nanoparticles Catalyzed One Pot Multicomponent Reaction
    Choudhary, Akanksha
    Verma, Monika
    Bharti, Ruchi
    Sharma, Renu
    CURRENT ORGANIC CHEMISTRY, 2025,
  • [35] Catalyst-Free Regio- and Diastereoselective Synthesis of Heterocyclic Nucleosides in the Eco-friendly Solvent 2-Methyltetrahydrofuran
    Gu, Xiaodong
    Du, Qingwei
    Song, Weijian
    Wang, Jun
    CHINESE JOURNAL OF CHEMISTRY, 2023, 41 (02): : 167 - 172
  • [36] Nano-TiO2: An Eco-Friendly and Clean Reusable Heterogeneous Catalyst for Preparation of α-Aminophosphonates Under Ambient and Solvent-Free Conditions
    Shaterian, Hamid Reza
    Farbodeh, Javad
    Mohammadnia, Majid
    PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2013, 188 (07) : 850 - 854
  • [37] Phenylboronic Acid as Efficient and Eco-Friendly Catalyst for the One-Pot, Three-Component Synthesis of α-Aminophosphonates under Solvent-Free Conditions
    Tibhe, Gaurao D.
    Bedolla-Medrano, Mercedes
    Cativiela, Carlos
    Ordonez, Mario
    SYNLETT, 2012, (13) : 1931 - 1936
  • [38] Facile, eco-friendly, catalyst-free synthesis of polyfunctionalized 2-aminopyrroles
    Yu, Wanwan
    Chen, Wenteng
    Liu, Shen
    Shao, Jiaan
    Shao, Zhanying
    Lin, Haili
    Yu, Yongping
    TETRAHEDRON, 2013, 69 (07) : 1953 - 1957
  • [39] An Eco-friendly, Hantzsch-Based, Solvent-Free Approach to 2-Aminothiazoles and 2-Aminoselenazoles
    Facchinetti, Victor
    Avellar, Marcela M.
    Nery, Ana C. S.
    Gomes, Claudia R. B.
    Vasconcelos, Thatyana R. A.
    de Souza, Marcus V. N.
    SYNTHESIS-STUTTGART, 2016, 48 (03): : 437 - 440
  • [40] An efficient, simple, and eco-friendly method for the synthesis of sydnone-containing Thiazoles under solvent-free conditions
    Kalluraya, B
    Rai, G
    SYNTHETIC COMMUNICATIONS, 2004, 34 (22) : 4055 - 4063
12345