The role of inflammation in ICU-acquired weakness

被引：16

作者：

Winkelman, Chris ^{[1
]}

机构：

[1] Case Western Reserve Univ, Frances Payne Bolton Sch Nursing, Cleveland, OH 44106 USA

来源：

CRITICAL CARE | 2010年 / 14卷 / 04期

关键词：

CRITICAL ILLNESS MYOPATHY; MUSCLE;

D O I：

10.1186/cc9187

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

A pilot observational study by Weber-Carstens and colleagues contributes to a mechanistic explanation of the puzzling and complex phenomena of ICU-acquired weakness (ICU-AW). The authors suggest systemic, inflammatory-mediated pathology is the most significant risk factor for ICU-AW. While this finding is somewhat equivocal, it provides important direction for future investigations and illustrates the challenges of interpreting significance in small observational studies.

引用

页数：2

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