The role of inflammation in ICU-acquired weakness

被引:0
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作者
Chris Winkelman
机构
[1] Case Western Reserve University,Frances Payne Bolton School of Nursing
来源
Critical Care | / 14卷
关键词
Myopathy; Sequential Organ Failure Assessment; Muscle Dysfunction; Muscle Stimulation; Muscle Pathology;
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摘要
A pilot observational study by Weber-Carstens and colleagues contributes to a mechanistic explanation of the puzzling and complex phenomena of ICU-acquired weakness (ICU-AW). The authors suggest systemic, inflammatory-mediated pathology is the most significant risk factor for ICU-AW. While this finding is somewhat equivocal, it provides important direction for future investigations and illustrates the challenges of interpreting significance in small observational studies.
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