The role of inflammation in ICU-acquired weakness

被引：16
|
作者：
Winkelman, Chris [1 ]
机构：
[1] Case Western Reserve Univ, Frances Payne Bolton Sch Nursing, Cleveland, OH 44106 USA
来源：
CRITICAL CARE | 2010年 / 14卷 / 04期
关键词：
CRITICAL ILLNESS MYOPATHY; MUSCLE;
D O I：
10.1186/cc9187
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
A pilot observational study by Weber-Carstens and colleagues contributes to a mechanistic explanation of the puzzling and complex phenomena of ICU-acquired weakness (ICU-AW). The authors suggest systemic, inflammatory-mediated pathology is the most significant risk factor for ICU-AW. While this finding is somewhat equivocal, it provides important direction for future investigations and illustrates the challenges of interpreting significance in small observational studies.
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页数：2
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