A continuous-flow mass biosensor for the real-time dynamic analysis of protease inhibition

被引：7
|
作者：
Huang, Yanyan [1 ]
Zhang, Qundan [1 ]
Liu, Guoquan [1 ]
Zhao, Rui [1 ]
机构：
[1] Chinese Acad Sci, Inst Chem, CAS Key Lab Analyt Chem Living Biosyst, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 30期
基金：
中国国家自然科学基金;
关键词：
QUARTZ-CRYSTAL MICROBALANCE; TURN-ON ASSAY; HUMAN SERUM; TRYPSIN; SURFACE; IMMOBILIZATION; CELLS; RECOGNITION; SUBSTRATE; RESONANCE;
D O I：
10.1039/c5cc00885a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A flow injection analysis-quartz crystal microbalance (FIA-QCM) biosensor was developed for probing the dynamic interactions during protease inhibition. Being sensitive to conformation features of different proteases, this continuous-flow sensor has potential for structural-functional analysis and inhibitor selection.
引用
收藏
页码：6601 / 6604
页数：4
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