Mechanisms of Toxic Effects of Homocysteine on the Nervous System

被引：3

作者：

Nevmerzhytska, N. M. ^{[1
]}

Orzheshkovskyi, V. V. ^{[2
]}

Dzevulska, I. V. ^{[1
]}

Savosko, S. I. ^{[1
]}

机构：

[1] Bogomolets Natl Med Univ, Kiev, Kiev, Ukraine

[2] Shupyk Natl Med Acad PostGrad Educ, Minist Publ Hlth Ukraine, Kiev, Kiev, Ukraine

来源：

NEUROPHYSIOLOGY | 2019年 / 51卷 / 05期

关键词：

homocysteine; hyperhomocysteinemia; toxic effects; pathogenesis; nervous system; CYSTATHIONINE BETA-SYNTHASE; PLASMA TOTAL HOMOCYSTEINE; FOLIC-ACID THERAPY; B-VITAMINS; PARKINSONS-DISEASE; PRIMARY PREVENTION; DNA METHYLATION; ISCHEMIC-STROKE; S-NITROSYLATION; CELL-ACTIVATION;

D O I：

10.1007/s11062-020-09832-x

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The review describes the metabolism of homocystein, causes of hyperhomocysteinemia, mechanisms underlying the respective negative effects on the nervous system, and main principles of correction of such disorders.

引用

页码：379 / 387

页数：9

共 50 条

[21] Neuroprotective effects of estrogens in the central nervous system: mechanisms of action
Behl, C
[J]. RISK AND PROTECTIVE FACTORS IN SCHIZOPHRENIA: TOWARDS A CONCEPTUAL MODEL OF THE DISEASE PROCESS, 2002, : 263 - 270
[22] Molecular Mechanisms Underlying the Effects of Statins in the Central Nervous System
McFarland, Amelia J.
Anoopkumar-Dukie, Shailendra
Arora, Devinder S.
Grant, Gary D.
McDermott, Catherine M.
Perkins, Anthony V.
Davey, Andrew K.
[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2014, 15 (11) : 20607 - 20637
[23] The effects on the central nervous system of nitroglycerin - Putative mechanisms and mediators
Tassorelli, C
Joseph, SA
Buzzi, MG
Nappi, G
[J]. PROGRESS IN NEUROBIOLOGY, 1999, 57 (06) : 607 - 624
[24] TOXIC EFFECTS OF LOCAL-ANESTHETIC AGENTS ON THE CENTRAL-NERVOUS-SYSTEM
SCOTT, DB
[J]. BRITISH JOURNAL OF ANAESTHESIA, 1986, 58 (07) : 732 - 735
[25] TOXIC EFFECTS OF ADRIAMYCIN ON GANGLIA OF PERIPHERIAL NERVOUS-SYSTEM - NEUROPATHOLOGICAL STUDY
CHO, ES
[J]. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1977, 36 (06): : 907 - 915
[26] TOXIC EFFECTS OF CHRONIC MERCURY EXPOSURE ON THE PERIPHERAL NERVOUS SYSTEM IN ELECTROCHEMICAL WORKERS
Ferrer Gonzalez, Yodeisy
del Toro Ramirez, Rodisnel
[J]. MUSCLE & NERVE, 2016, 54 (03) : 543 - 543
[27] NERVOUS SYSTEM - AFFERENT MECHANISMS
GOLDBERG, JM
LAVINE, RA
[J]. ANNUAL REVIEW OF PHYSIOLOGY, 1968, 30 : 319 - +
[28] INTEGRATIVE MECHANISMS IN THE NERVOUS SYSTEM
FUORTES, MGF
[J]. AMERICAN NATURALIST, 1959, 93 (871): : 213 - 224
[29] A review of cumulative toxic effects of environmental endocrine disruptors on the zebrafish immune system: Characterization methods, toxic effects and mechanisms
Li, Zixu
Li, Muge
Li, Dan
Chen, Yao
Feng, Weiwei
Zhao, Ting
Yang, Liuqing
Mao, Guanghua
Wu, Xiangyang
[J]. ENVIRONMENTAL RESEARCH, 2024, 246
[30] BIOCHEMICAL ACTIONS OF TOXIC SUBSTANCES ON THE NERVOUS SYSTEM
Elliott, K. A. C.
[J]. RESEARCH PUBLICATIONS-ASSOCIATION FOR RESEARCH IN NERVOUS AND MENTAL DISEASE, 1953, 32 : 422 - 431

← 1 2 3 4 5 →